Gastric pressure response to low dose dopamine infusion in normal man.

Gastric pressure response to low dose dopamine infusion in normal man. Research Abstract Details 

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Gastric pressure response to low dose dopamine infusion in normal man. Abstract Text:

M N Hartley,R F Sarginson,C J Green,N J Parr,R Duckworth,P F Maycock,J A Fairhurst,I T Campbell,

The gastric pressure response to distension was measured during intravenous infusion of dopamine at a rate of 2 mug min(-1)kg(-1) over 2h 50min in 5 normal volunteers to determine whether dopamine at this dose potentiated gastric adaptive relaxation, leading to a fall in gastric pressure and thus a potential delay in gastric emptying. This would be of obvious importance in patients being given dopamine at this dose to support renal function and at the same time being fed by nasogastric tube. The pressure response decreased during the first hour in all five subjects (p < 0.01). In 2 it recovered during the third hour to pre-infusion values, but in 2 it remained diminished; in 1 subject the results were equivocal. Circulating dopamine, noradrenaline and adrenaline concentrations all increased during dopamine (p < 0.05), but compared with control there was no difference in plasma free fatty acids, glycerol, cortisol or glucose concentrations. Dopamine at 2 mug min(-1) kg(-1) produced a transient fall in gastric pressure in all subjects, and a persistent fall in some. The changes in gastric pressures were seen at infusion rates that produced no metabolic or inotropic effects.

Gastric pressure response to low dose dopamine infusion in normal man. Publishing Authors By Initials

MN Hartley,RF Sarginson,CJ Green,NJ Parr,R Duckworth,PF Maycock,JA Fairhurst,IT Campbell,

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Gastric pressure response to low dose dopamine infusion in normal man. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Clinical nutrition (Edinburgh, Scotland)

VOLUME: 11

Page Numbers: 23-9

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ISSN: 0261-5614

DAY: 14

MONTH: Feb

YEAR: 1992

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LANGUAGE: eng

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Grant and Affiliation Information for Gastric pressure response to low dose dopamine infusion in normal man.

AFFILIATION: University Department of Anaesthesia, Royal Liverpool Hospital, Liverpool, UK.

Country: England

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MEDLINETA: Clin Nutr

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