Gastric lymphomas: aspects of follow-up and after-care.

Gastric lymphomas: aspects of follow-up and after-care. Research Abstract Details 

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Gastric lymphomas: aspects of follow-up and after-care. Abstract Text:

W Heise,

In recent years, new insights into gastric lymphomas and their etiology and pathogenesis have been gained. The predominant role of infection with Helicobacter pylori in the pathogenesis as a pre-malignant condition of a special lymphoma entity [gastric lymphoma of the mucosa-associated lymphoid tissue (MALT) type], has defined new diagnostic procedures and concepts of treatment. Therefore, prognostic factors (e.g. stage of lymphoma, histopathologic grading, resectability etc.) are extremely important for the intensity and efficacy of follow-up and after-care. Surveillance programs in gastric lymphoma include sequelae of surgical resection, chemotherapy and radiotherapy, and the efficacy of follow-up procedures have to be measured by the prevention of tumor relapse in comparison to the intensity of diagnostic procedures. Since lymphoma relapse may occur both as local or disseminated recurrence in 13%-35% of cases, follow-up procedures have to regard both aspects during surveillance. While these follow-up programs are standardized in epithelial tumors (e.g. colon carcinoma), they are not yet established or comparable for each type of gastric lymphoma. Low-grade MALT lymphomas have to be considered as a new lymphoma entity. In addition, new diagnostic procedures (e.g. molecular parameters such as polymerase chain reaction (PCR) for clonality, endosonography, "gastric mapping") have been found to be important parameters for diagnosis and staging of gastric lymphoma and may therefore be relevant for the course of the disease. The definition of "lymphoma cure" and the impact of these procedures as prognostic factors will have to be discussed and may influence the follow-up of gastric lymphoma.

Gastric lymphomas: aspects of follow-up and after-care. Publishing Authors By Initials

W Heise,

For similar surgical procedures, operative research abstracts see: surgical procedures, operative research

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Gastric lymphomas: aspects of follow-up and after-care. Journal Published:

PUBLICATION TYPE: Review

Journal: Recent results in cancer research. Fortschritte de

VOLUME: 156

Page Numbers: 69-77

Journal Abbreviation: Recent Results Cancer Res.

ISSN: 0080-0015

DAY: 13

MONTH: 02

YEAR: 2000

Gastric lymphomas: aspects of follow-up and after-care. Information

Number of References: 26

LANGUAGE: eng

NlmUniqueID: 44671

Gastric lymphomas: aspects of follow-up and after-care. Keywords Mesh Terms:

KEYWORDS: Surgical Procedures, Operative

MESH TERMS: therapy

Chemical & Substance for Abstract: Gastric lymphomas: aspects of follow-up and after-care. Information

Substance Name: Antineoplastic Agents

Registry Number: 0

Grant and Affiliation Information for Gastric lymphomas: aspects of follow-up and after-care.

AFFILIATION: Auguste-Viktoria-Hospital, Klinikum Benjamin Franklin, Freie Universität Berlin, Germany.

Country: GERMANY

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MEDLINETA: Recent Results Cancer Res

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