Gastric adenocarcinoma arising from fundic gland polyps in a patient with familial adenomatous polyposis syndrome.

Gastric adenocarcinoma arising from fundic gland polyps in a patient with familial adenomatous polyposis syndrome. Research Abstract Details 

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Gastric adenocarcinoma arising from fundic gland polyps in a patient with familial adenomatous polyposis syndrome. Abstract Text:

Sean Garrean,Justin Hering,Abdul Saied,Jigna Jani,N Joseph Espat,

Familial adenomatous polyposis (FAP) is a rare hereditary syndrome characterized by multiple colorectal polyps and early development of colorectal cancer. Although FAP uniformly involves the large bowel, it may also produce lesions in the stomach and upper intestinal tract. Fundic gland polyps are the most common gastric lesion in FAP. In the general population, these polyps are considered benign and have no malignant potential. However, in FAP patients, fundic gland polyps have been occasionally recognized as precursor lesions from which invasive cancer may develop. Herein, we present a case of gastric adenocarcinoma arising from fundic gland polyps in an FAP patient. We also review reported cases of gastric cancer in FAP and FAP variant patients in an effort to better understand the pathology, clinical course, and optimal screening and treatment strategies for this disease manifestation.

Gastric adenocarcinoma arising from fundic gland polyps in a patient with familial adenomatous polyposis syndrome. Publishing Authors By Initials

S Garrean,J Hering,A Saied,J Jani,NJ Espat,

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Gastric adenocarcinoma arising from fundic gland polyps in a patient with familial adenomatous polyposis syndrome. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The American surgeon

VOLUME: 74

Page Numbers: 79-83

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ISSN: 0003-1348

DAY: 15

MONTH: Jan

YEAR: 2008

Gastric adenocarcinoma arising from fundic gland polyps in a patient with familial adenomatous polyposis syndrome. Information

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LANGUAGE: eng

NlmUniqueID: 370522

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Grant and Affiliation Information for Gastric adenocarcinoma arising from fundic gland polyps in a patient with familial adenomatous polyposis syndrome.

AFFILIATION: Department of Surgery, University of Illinois at Chicago, Chicago, Illinois, USA.

Country: United States

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MEDLINETA: Am Surg

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