[Gallstones--natural history and conservative management]

[Gallstones--natural history and conservative management] Research Abstract Details 

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[Gallstones--natural history and conservative management] Abstract Text:

J Reichen,

Gallstones have a very high prevalence affecting 9.5 and 19.5% of men and women, respectively. The pathophysiology and risk factors for cholesterol gallstones are considered. Modern imaging techniques, in particular ultrasound, are very sensitive to detect cholecystolithiasis, while ERCP remains the gold standard to detect choledocholithiasis. ERCP could be supplanted soon by endosonography and MRCP. Biliary scintigraphy is useful to detect a 'vésicule exclue' and to document gallbladder/sphincter Oddi dysfunction. The different conservative management strategies including litholytic treatment with ursodeoxycholate and lithotripsy have been largely abandoned in favor of laparoscopic cholecystectomy. Litholytic treatment has still a role to play in the prevention of gallstone formation in patients with rapid weight loss and in the newly detected MDR3 defect associated with sludge formation. Biliary colic is treated with non-steroidal analgesic drugs, analgesics and/or spasmolytic agents.

[Gallstones--natural history and conservative management] Publishing Authors By Initials

J Reichen,

For similar polycyclic compounds: steroids: bile acids and salts: cholic acids: deoxycholic acid: ursodeoxycholic acid research abstracts see: polycyclic compounds: steroids: bile acids and salts: cholic acids: deoxycholic acid: ursodeoxycholic acid research

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[Gallstones--natural history and conservative management] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Therapeutische Umschau. Revue thérapeutique

VOLUME: 60

Page Numbers: 109-12

Journal Abbreviation:

ISSN: 0040-5930

DAY: 12

MONTH: Feb

YEAR: 2003

[Gallstones--natural history and conservative management] Information

Number of References:

LANGUAGE: ger

NlmUniqueID: 407224

[Gallstones--natural history and conservative management] Keywords Mesh Terms:

KEYWORDS: Ursodeoxycholic Acid

MESH TERMS: adverse effects

Chemical & Substance for Abstract: [Gallstones--natural history and conservative management] Information

Substance Name: Cholesterol

Registry Number: 57-88-5

Grant and Affiliation Information for [Gallstones--natural history and conservative management]

AFFILIATION: Institut für Klinische Pharmakologie, Universität Bern. reichen@ikp.unibe.ch

Country: Switzerland

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ACRONYM:

MEDLINETA: Ther Umsch

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