Fungal biofilm inhibition by a component naturally produced by Candida albicans yeasts growing as a biofilm.

Fungal biofilm inhibition by a component naturally produced by Candida albicans yeasts growing as a biofilm. Research Abstract Details 

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Fungal biofilm inhibition by a component naturally produced by Candida albicans yeasts growing as a biofilm. Abstract Text:

Estelle Cateau,Jean-Marc Berjeaud, Rodier,Christine Imbert,

The purpose of this work was to demonstrate production by the Candida yeasts growing as a biofilm of a compound that reduces candidal biofilm growth. An in vitro model of Candida albicans biofilm associated with silicone catheters was used. Supernatant medium recovered from 24-h-old C. albicans (ATCC 3153) biofilm (S24h) was added during the course of new biofilm formation by four C. albicans strains (182, 444, 2091 or ATCC 3153). Addition of S24h to adherent C. albicans cells induced an inhibition of biofilm growth (P<0.001) but displayed no activity on established biofilms. Ultrafiltration and purification assays demonstrated that the antagonistic molecule is hydrophilic and <3000Da in size.

Fungal biofilm inhibition by a component naturally produced by Candida albicans yeasts growing as a biofilm. Publishing Authors By Initials

E Cateau,JM Berjeaud,MH Rodier,C Imbert,

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Fungal biofilm inhibition by a component naturally produced by Candida albicans yeasts growing as a biofilm. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: International journal of antimicrobial agents

VOLUME: 31

Page Numbers: 166-70

Journal Abbreviation: Int. J. Antimicrob. Agents

ISSN: 0924-8579

DAY: 21

MONTH: 12

YEAR: 2007

Fungal biofilm inhibition by a component naturally produced by Candida albicans yeasts growing as a biofilm. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Fungal biofilm inhibition by a component naturally produced by Candida albicans yeasts growing as a biofilm.

AFFILIATION: Equipe de Parasitologie et Mycologie Médicales, LCEE, Université de Poitiers, UMR 6008, 6 Rue de la Milètrie, BP 199, 86034 Poitiers cedex et CHU de Poitiers, France.

Country: Netherlands

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MEDLINETA: Int J Antimicrob Agents

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