Functional role of unmyelinated tactile afferents in human hairy skin: sympathetic response and perceptual localization.

Functional role of unmyelinated tactile afferents in human hairy skin: sympathetic response and perceptual localization. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Functional role of unmyelinated tactile afferents in human hairy skin: sympathetic response and perceptual localization. Abstract Text:

Olausson,Jonathan Cole,Karin Rylander,Francis McGlone,Yves Lamarre,B Gunnar Wallin,Heidrun ,Johan Wessberg,Mikael Elam,M Catherine Bushnell,Ake Vallbo, Olausson,Jonathan Cole,Karin Rylander,Francis McGlone,Yves Lamarre,B Gunnar Wallin,Heidrun ,Johan Wessberg,Mikael Elam,M Catherine Bushnell,Ake Vallbo,

In addition to A-beta fibres the human hairy skin has unmyelinated (C) fibres responsive to light touch. Previous functional magnetic resonance imaging (fMRI) studies in a subject with a neuronopathy who specifically lacks A-beta afferents indicated that tactile C afferents (CT) activate insular cortex, whereas no response was seen in somatosensory areas 1 and 2. Psychophysical tests suggested that CT afferents give rise to an inconsistent perception of weak and pleasant touch. By examining two neuronopathy subjects as well as control subjects we have now demonstrated that CT stimulation can elicit a sympathetic skin response. Further, the neuronopathy subjects' ability to localize stimuli which activate CT afferents was very poor but above chance level. The findings support the interpretation that the CT system is well suited to underpin affective rather than discriminative functions of tactile sensations.

Functional role of unmyelinated tactile afferents in human hairy skin: sympathetic response and perceptual localization. Publishing Authors By Initials

H Olausson,J Cole,K Rylander,F McGlone,Y Lamarre,BG Wallin,H ,J Wessberg,M Elam,MC Bushnell,A Vallbo,H Olausson,J Cole,K Rylander,F McGlone,Y Lamarre,BG Wallin,H ,J Wessberg,M Elam,MC Bushnell,A Vallbo,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Functional role of unmyelinated tactile afferents in human hairy skin: sympathetic response and perceptual localization. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Experimental brain research. Experimentelle Hirnf

VOLUME: 184

Page Numbers: 135-40

Journal Abbreviation:

ISSN: 0014-4819

DAY: 26

MONTH: 10

YEAR: 2007

Functional role of unmyelinated tactile afferents in human hairy skin: sympathetic response and perceptual localization. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 43312

Functional role of unmyelinated tactile afferents in human hairy skin: sympathetic response and perceptual localization. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Functional role of unmyelinated tactile afferents in human hairy skin: sympathetic response and perceptual localization. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Functional role of unmyelinated tactile afferents in human hairy skin: sympathetic response and perceptual localization.

AFFILIATION: Department of Clinical Neurophysiology, Sahlgrenska University Hospital, Blå stråket 7, 413 45, Göteborg, Sweden, olausson@physiol.gu.se.

Country: Germany

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Exp Brain Res

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Functional role of unmyelinated tactile afferents in human hairy skin: sympathetic response and perceptual localization Related Publications

• Activity in human muscle afferents during muscle stretch and contraction.
• Functional role of unmyelinated tactile afferents in human hairy skin: sympathetic response and perceptual localization.
• STUDIES IN THE PSYCHOLOGICAL EFFECTS OF A NEW DRUG (DIETHYLPROPION). SUBJECTIVE EFFECTS IN THE NATURAL ENVIRONMENT.