Functional consequences of retinopetal fibers originating in the dorsal raphe nucleus.

Functional consequences of retinopetal fibers originating in the dorsal raphe nucleus. Research Abstract Details 

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Functional consequences of retinopetal fibers originating in the dorsal raphe nucleus. Abstract Text:

The existence of centrifugal fibers projecting into the mammalian retina is well known. However, their precise physiological role is poorly understood. Here we report that stimulation of the dorsal raphe nucleus (DRN) in freely moving rats produces profound effects on the electroretinogram (ERG). Most notably, activation of the dorsal raphe-retinal pathway causes a significant decrease in the latency of the b-wave and accompanying oscillatory potentials. In addition, dorsal raphe stimulation leads to a significant increase in the amplitude of oscillatory potentials. These results, therefore, provide the first demonstration of a functional role for the retinopetal fiber system originating in the and suggest that this structure can exert a powerful influence over the temporal sharpness and efficacy of retinal responsiveness.

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Functional consequences of retinopetal fibers originating in the dorsal raphe nucleus. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The International journal of neuroscience

VOLUME: 118

Page Numbers: 1374-83

Journal Abbreviation: Int. J. Neurosci.

ISSN: 1563-5279

DAY: 12

MONTH: Oct

YEAR: 2008

Functional consequences of retinopetal fibers originating in the dorsal raphe nucleus. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Functional consequences of retinopetal fibers originating in the dorsal raphe nucleus.

AFFILIATION: Neurobiology Research Group, Hungarian Academy of Sciences, Eotvos Lorand University, Budapest, Hungary.

Country: United States

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MEDLINETA: Int J Neurosci

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