From tau to toxicity: emerging roles of NMDA receptor in Alzheimer's disease.

From tau to toxicity: emerging roles of NMDA receptor in Alzheimer's disease. Research Abstract Details 

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From tau to toxicity: emerging roles of NMDA receptor in Alzheimer's disease. Abstract Text:

Muhammad Omar Chohan,Khalid Iqbal,

Glutamate toxicity through NMDA receptor channels has long been central to the understanding of acute neuronal injury. Recent studies implicate similar events in chronic neurodegenerative diseases. Here, we analyze some of the most intriguing evidence for NMDA receptor-mediated cellular dysfunction and propose a mechanism by which hyperactive NMDA receptors might lead to neurofibrillary degeneration in Alzheimer's disease.

From tau to toxicity: emerging roles of NMDA receptor in Alzheimer's disease. Publishing Authors By Initials

MO Chohan,K Iqbal,

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From tau to toxicity: emerging roles of NMDA receptor in Alzheimer's disease. Journal Published:

PUBLICATION TYPE: Review

Journal: Journal of Alzheimer's disease : JAD

VOLUME: 10

Page Numbers: 81-7

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ISSN: 1387-2877

DAY: 3

MONTH: Sep

YEAR: 2006

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LANGUAGE: eng

NlmUniqueID: 9814863

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Grant and Affiliation Information for From tau to toxicity: emerging roles of NMDA receptor in Alzheimer's disease.

AFFILIATION: Department of Neurochemistry, New York State Institute for Basic Research in Developmental Disabilities, 1050 Forest Hill Road, Staten Island, New York 10314-6399, USA. Muhammad.chohan@omr.state.ny.us

Country: Netherlands

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MEDLINETA: J Alzheimers Dis

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