Frequency spectrum and amplitude analysis of dark- and light-adapted oscillatory potentials in albino mouse, rat and rabbit.

Frequency spectrum and amplitude analysis of dark- and light-adapted oscillatory potentials in albino mouse, rat and rabbit. Research Abstract Details 

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Frequency spectrum and amplitude analysis of dark- and light-adapted oscillatory potentials in albino mouse, rat and rabbit. Abstract Text:

Keqing Zhang,Gang Yao,Yuanfang Gao,Kurt J Hofeldt,Bo Lei,Keqing Zhang,Gang Yao,Yuanfang Gao,Kurt J Hofeldt,Bo Lei,Keqing Zhang,Gang Yao,Yuanfang Gao,Kurt J Hofeldt,Bo Lei,

We studied frequency spectrum, implicit time and amplitude of oscillatory potentials (OPs) in albino mice, rats, and rabbits. Oscillatory potentials were extracted digitally from dark- and light-adapted electroretinograms (ERGs) recorded with a protocol commonly used in our laboratory. The frequency spectra of OPs were analyzed by using Fast Fourier Transform (FFT). Oscillatory potential amplitudes were calculated via numerically integrating the power spectrum. Oscillatory potential frequency spectra vary among species and are light-intensity dependent. In dark-adapted ERG, mouse and rat OPs have one major component with a frequency peak at approximately 100 Hz. Rabbits show multiple frequency peaks with a low frequency peak around 75 Hz. In all the three species, the implicit time of light-adapted OP is longer than that of the dark-adapted OPs. At a given intensity, mice have the highest OP responses. Our data suggest that the commonly used bandpass of 75 Hz (or even 100 Hz) to 300 Hz for OP extraction is insufficient in these animals. In order to acquire the complete OP responses from the ERG signals, it is necessary to determine the OP frequency spectrum. In this study, the lower end cutoff frequency was set at 40 Hz in mice, 65 Hz in rats and rabbits.

Frequency spectrum and amplitude analysis of dark- and light-adapted oscillatory potentials in albino mouse, rat and rabbit. Publishing Authors By Initials

K Zhang,G Yao,Y Gao,KJ Hofeldt,B Lei,K Zhang,G Yao,Y Gao,KJ Hofeldt,B Lei,K Zhang,G Yao,Y Gao,KJ Hofeldt,B Lei,

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Frequency spectrum and amplitude analysis of dark- and light-adapted oscillatory potentials in albino mouse, rat and rabbit. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Documenta ophthalmologica. Advances in ophthalmolo

VOLUME: 115

Page Numbers: 85-93

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ISSN: 0012-4486

DAY: 1

MONTH: 06

YEAR: 2007

Frequency spectrum and amplitude analysis of dark- and light-adapted oscillatory potentials in albino mouse, rat and rabbit. Information

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LANGUAGE: eng

NlmUniqueID: 370667

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Grant and Affiliation Information for Frequency spectrum and amplitude analysis of dark- and light-adapted oscillatory potentials in albino mouse, rat and rabbit.

AFFILIATION: Department of Veterinary and Surgery, University of Missouri-Columbia, Columbia, MO, 65211, USA.

Country: Netherlands

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MEDLINETA: Doc Ophthalmol

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