Frequency of malignant solid tumors in children.

Frequency of malignant solid tumors in children. Research Abstract Details 

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Frequency of malignant solid tumors in children. Abstract Text:

S H Shah,S Pervez,S H Hassan,

OBJECTIVE: To find out the frequency of malignant solid tumors in children (< 15 years). SETTING: All cases of pediatric malignant solid tumors which were diagnosed in the section of histopathology at the Aga Khan University Hospital, Karachi during the period of two years. METHODS: These tumors were initially evaluated on H&E stained sections and special stains were also performed whenever indicated. The undifferentiated tumors were evaluated immunohistochemically by using a panel of antibodies on sections from routinely processed, formalin fixed, paraffin embedded tissue blocks. RESULTS: Of two hundred and fifty three (253) consecutive cases of paediatric malignant solid tumors, lymphoma (26.1%) was the most common tumor followed by central nervous system tumors (16.6%), osteosarcoma (7.5%), rhabdomyosarcoma (6.7%), neuroblastoma (5.1%), Wilm's tumor (5.1%), Ewing's sarcoma (4.7%), retinoblastoma (4.7%), germ cell tumor (4.4%) and primitive neuroectodermal tumor (4%) in order of frequency. In seven cases (2.8%), the nature of lesion remained undetermined even after immunohistochemical staining. Rest of malignant tumors (12.3%) included the rare entities like synovial sarcoma, nasopharyngeal carcinoma, leiomyosarcoma, malignant schwannoma and thyroid carcinoma, etc. CONCLUSION: Lymphoma was the most frequent Paediatric tumor. The frequency of childhood central nervous system tumors was quite high as compared to the other series from different regions of Pakistan.

Frequency of malignant solid tumors in children. Publishing Authors By Initials

SH Shah,S Pervez,SH Hassan,

For similar geographic locations: asia: asia, western: pakistan research abstracts see: geographic locations: asia: asia, western: pakistan research

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Frequency of malignant solid tumors in children. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: JPMA. The Journal of the Pakistan Medical Associat

VOLUME: 50

Page Numbers: 86-8

Journal Abbreviation:

ISSN: 0030-9982

DAY: 12

MONTH: Mar

YEAR: 2000

Frequency of malignant solid tumors in children. Information

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LANGUAGE: eng

NlmUniqueID: 7501162

Frequency of malignant solid tumors in children. Keywords Mesh Terms:

KEYWORDS: Pakistan

MESH TERMS: epidemiology

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Grant and Affiliation Information for Frequency of malignant solid tumors in children.

AFFILIATION: Department of Pathology, Aga Khan University Hospital, Karachi.

Country: PAKISTAN

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MEDLINETA: J Pak Med Assoc

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