Fragments of immunoglobulins in human faeces.

Fragments of immunoglobulins in human faeces. Research Abstract Details 

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Fragments of immunoglobulins in human faeces. Abstract Text:

Fab-fragments of IgG were easily demonstrated in extracts of faeces from healthy infants and children. Employing immunoelectrophoresis with antisera to whole human serum and to Fab-fragments of IgG, a marked precipitation line, likely to represent such fragments, was evident in the cathodal or gamma-region. Usually no precipitate was formed with antisera specific for gamma-heavy chains or Fc-fragments of IgG. Presumably IgG in the gut is partially destroyed before being excreted with faeces. Results of immunoelectrophoresis, gel filtration as well as polyacrylamide gel electrophoresis, using antisera to alpha-heavy chains, indicated the presence of fragments of IgA in some faecal extracts. Fragments of IgA could not be demonstrated in IgA-deficient patients, and no fragments of either class, or only traces of Fab-fragments of IgG, were found in agammaglobulinaemic patients. No antibody activity against rabbit erythrocytes was found in gel filtrations containing such fragments; any reaction was not observed either in the direct agglutination test or in a modified antiglobulin test.

Fragments of immunoglobulins in human faeces. Publishing Authors By Initials

For similar persons: age groups: infant research abstracts see: persons: age groups: infant research

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Fragments of immunoglobulins in human faeces. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Acta pathologica et microbiologica Scandinavica. S

VOLUME: 84

Page Numbers: 31-6

Journal Abbreviation:

ISSN: 0304-1328

DAY: 26

MONTH: Feb

YEAR: 1976

Fragments of immunoglobulins in human faeces. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7508469

Fragments of immunoglobulins in human faeces. Keywords Mesh Terms:

KEYWORDS: Infant

MESH TERMS: analysis

Chemical & Substance for Abstract: Fragments of immunoglobulins in human faeces. Information

Substance Name: Immunoglobulin G

Registry Number: 0

Grant and Affiliation Information for Fragments of immunoglobulins in human faeces.

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Country: DENMARK

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MEDLINETA: Acta Pathol Microbiol Scand [C

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