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Forefoot vasoconstrictor response to increased venous pressure in normal subjects and in arteriosclerotic patients.

Forefoot vasoconstrictor response to increased venous pressure in normal subjects and in arteriosclerotic patients. Research Abstract Details 

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  • Forefoot vasoconstrictor response to increased venous pressure in normal subjects and in arteriosclerotic patients. Abstract Text:

    j h eickhoffJ H Eickhoff,

    The local vasoconstrictor response to increased venous transmural pressure was studied in the forefoot in 18 normal subjects and in 43 patients with occlusive arterial disease of the lower limbs. Subcutaneous blood flow was measured by the local 133-Xenon wash-out technique. Blood flow measured 40 cm below heart level was compared to blood flow measured at heart level. In 18 normal limbs the vasoconstrictor response caused a decrease in blood flow to a median value of 73%, compared to a median value of 88% in 22 limbs with intermittent claudication without rest pain (p = 0.01). In limbs with ischemic symptoms at rest blood flow increased to a median value of 1.36, when the leg was lowered. Assuming that arterial and venous transmural pressures increase equally during lowering, corresponding to the hydrostatic pressure, keeping the perfusion pressure constant, then the changes in blood flow are due to changes in local peripheral resistance. The significantly smaller decrease in blood flow in claudicants is thus interpreted being due to a functional or structural adaptation of the arterioles to the chronic hypotension. The increase in blood flow during lowering in limbs with rest pain implies a diminished peripheral resistance caused by passive dilation of the arterioles by the increased transmural pressure.

    Forefoot vasoconstrictor response to increased venous pressure in normal subjects and in arteriosclerotic patients. Publishing Authors By Initials

    jh eickhoffJH Eickhoff,

    For similar inorganic chemicals: isotopes: radioisotopes: xenon radioisotopes research abstracts see: inorganic chemicals: isotopes: radioisotopes: xenon radioisotopes research

    PUBMED ID PMID:

    MEDLINE DATE:

    Forefoot vasoconstrictor response to increased venous pressure in normal subjects and in arteriosclerotic patients. Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: Acta chirurgica Scandinavica. Supplementum

    VOLUME: 502

    Page Numbers: 7-14

    Journal Abbreviation:

    ISSN: 0301-1860

    DAY: 6

    MONTH: 12

    YEAR: 1980

    Forefoot vasoconstrictor response to increased venous pressure in normal subjects and in arteriosclerotic patients. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 370305

    Forefoot vasoconstrictor response to increased venous pressure in normal subjects and in arteriosclerotic patients. Keywords Mesh Terms:

    KEYWORDS: Xenon Radioisotopes

    MESH TERMS: diagnostic use

    Chemical & Substance for Abstract: Forefoot vasoconstrictor response to increased venous pressure in normal subjects and in arteriosclerotic patients. Information

    Substance Name: Xenon Radioisotopes

    Registry Number: 0

    Grant and Affiliation Information for Forefoot vasoconstrictor response to increased venous pressure in normal subjects and in arteriosclerotic patients.

    AFFILIATION:

    Country: SWEDEN

    SWEDEN Research PublicationSWEDEN Research Publication

    AGENCY:

    GRANT:

    ACRONYM:

    MEDLINETA: Acta Chir Scand Suppl

    REFSOURCE:

    DATABASENAME:

    ACCESSION NUMBER:

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