Follicular dendritic cell sarcoma of lymph node--a rare entity.

Follicular dendritic cell sarcoma of lymph node--a rare entity. Research Abstract Details 

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Follicular dendritic cell sarcoma of lymph node--a rare entity. Abstract Text:

Safoorah Khalid,Nausheen Yaqoob,Shahid Pervez,

Follicular dendritic cells (FDC) are non-lymphoid, non-phagocytic accessory cells in the immune system that are essential for antigen presentation and germinal center reaction regulation. These cells are CD21+, CD35+, CD1a- and S100 protein +/- and they show desmosomes ultrastructurally. The most commonly involved sites by FDC tumors are lymph nodes but may arise at a variety of extranodal sites including oral cavity, tonsil, gastrointestinal tract and liver. Most studies represent single case reports or case series. Our patient presented with tumor in the lymph nodes. Histology revealed tumor cells with abundant eosinophilic cytoplasm, hyperchromatic and pleomorphic nuclei, and prominent nucleoli. The tumor cells were found to be positive for CD21 which is a specific marker for follicular dendritic cells.

Follicular dendritic cell sarcoma of lymph node--a rare entity. Publishing Authors By Initials

S Khalid,N Yaqoob,S Pervez,

For similar biological factors: biological markers: tumor markers, biological research abstracts see: biological factors: biological markers: tumor markers, biological research

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Follicular dendritic cell sarcoma of lymph node--a rare entity. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: JPMA. The Journal of the Pakistan Medical Associat

VOLUME: 56

Page Numbers: 137-9

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ISSN: 0030-9982

DAY: 12

MONTH: Mar

YEAR: 2006

Follicular dendritic cell sarcoma of lymph node--a rare entity. Information

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LANGUAGE: eng

NlmUniqueID: 7501162

Follicular dendritic cell sarcoma of lymph node--a rare entity. Keywords Mesh Terms:

KEYWORDS: Tumor Markers, Biological

MESH TERMS: analysis

Chemical & Substance for Abstract: Follicular dendritic cell sarcoma of lymph node--a rare entity. Information

Substance Name: Tumor Markers, Biological

Registry Number: 0

Grant and Affiliation Information for Follicular dendritic cell sarcoma of lymph node--a rare entity.

AFFILIATION: Department of Pathology and Microbiology, The Aga Khan University, Karachi.

Country: Pakistan

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MEDLINETA: J Pak Med Assoc

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