Focal uptake of (18)F-fluorodeoxyglucose by thyroid in patients with nonthyroidal head and neck cancers.

Focal uptake of (18)F-fluorodeoxyglucose by thyroid in patients with nonthyroidal head and neck cancers. Research Abstract Details 

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Focal uptake of (18)F-fluorodeoxyglucose by thyroid in patients with nonthyroidal head and neck cancers. Abstract Text:

Soon Yuhl Nam,Jong-Lyel Roh,Jae Seung Kim,Jeong Hyun Lee,Seung-Ho Choi,Sang Yoon Kim,

OBJECTIVE: To evaluate the prevalence and significance of focal thyroid lesions identified by (18)F-fluorodeoxyglucose (FDG)-positron emission tomography (PET) in patients with nonthyroidal head and neck cancers (HNC). PATIENTS AND MEASUREMENTS: Patients with histologically identified HNC who underwent FDG-PET and computed tomography (CT) were reviewed retrospectively. We evaluated the prevalence of patients with focal thyroid FDG uptake and the risk of malignancy and proper management in these patients. RESULTS: Of 689 HNC patients, 19 (2.8%) had focal thyroid FDG uptake. Of the 12 patients with a histological diagnosis by surgery or needle biopsy, 5 (41.7%) had carcinomas, 4 papillary and 1 follicular, whereas the others had benign thyroid lesions. The maximum standardized uptake value on PET was not sufficient to discriminate between malignant and benign thyroid lesions (8.4 +/- 13.2 vs. 4.2 +/- 4.0; P > 0.4). The identification of incidental thyroid diseases helped guide patient counselling and combined surgery with HNC and thyroidectomy. CONCLUSION: Focal thyroid lesions incidentally found on FDG-PET in patents with nonthyroidal HNC have a high probability of malignancy. These lesions deserve further diagnostic examination before HNC treatment to ensure adequate therapy for incidental thyroid cancers.

Focal uptake of (18)F-fluorodeoxyglucose by thyroid in patients with nonthyroidal head and neck cancers. Publishing Authors By Initials

SY Nam,JL Roh,JS Kim,JH Lee,SH Choi,SY Kim,

For similar tomography, x-ray computed research abstracts see: tomography, x-ray computed research

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Focal uptake of (18)F-fluorodeoxyglucose by thyroid in patients with nonthyroidal head and neck cancers. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Clinical endocrinology

VOLUME: 67

Page Numbers: 135-9

Journal Abbreviation: Clin. Endocrinol. (Oxf)

ISSN: 0300-0664

DAY: 27

MONTH: 04

YEAR: 2007

Focal uptake of (18)F-fluorodeoxyglucose by thyroid in patients with nonthyroidal head and neck cancers. Information

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LANGUAGE: eng

NlmUniqueID: 346653

Focal uptake of (18)F-fluorodeoxyglucose by thyroid in patients with nonthyroidal head and neck cancers. Keywords Mesh Terms:

KEYWORDS: Tomography, X-Ray Computed

MESH TERMS: radionuclide imaging

Chemical & Substance for Abstract: Focal uptake of (18)F-fluorodeoxyglucose by thyroid in patients with nonthyroidal head and neck cancers. Information

Substance Name: Fluorodeoxyglucose F18

Registry Number: 63503-12-8

Grant and Affiliation Information for Focal uptake of (18)F-fluorodeoxyglucose by thyroid in patients with nonthyroidal head and neck cancers.

AFFILIATION: Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

Country: England

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MEDLINETA: Clin Endocrinol (Oxf)

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