Focal enhancement of cranial nerve V after radiosurgery with the Leksell gamma knife: experience in 15 patients with medically refractory trigeminal neuralgia.

Focal enhancement of cranial nerve V after radiosurgery with the Leksell gamma knife: experience in 15 patients with medically refractory trigeminal neuralgia. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Focal enhancement of cranial nerve V after radiosurgery with the Leksell gamma knife: experience in 15 patients with medically refractory trigeminal neuralgia. Abstract Text:

R A Alberico,R A Fenstermaker,J Lobel,

BACKGROUND AND PURPOSE: Gamma knife radiosurgery is an alternative for the treatment of medically refractory trigeminal neuralgia. Few reports of posttreatment MR imaging appearance of cranial nerve V exist. Our purpose was to define MR imaging characteristics in cranial nerve V after gamma knife radiosurgery. METHODS: We retrospectively reviewed MR images of 15 patients who underwent gamma knife radiosurgery for trigeminal neuralgia. Radiation doses were 35-45 Gy at the 50% isodose line. Thin-section T2-weighted images and contrast-enhanced and nonenhanced T1-weighted images were obtained the day of radiosurgery and within the next 5 mo. Images were scored for enhancement and hyperintensity on T2-weighted images. Time to follow-up imaging and radiation dose were recorded. RESULTS: Mean time to follow-up imaging was 61 +/- 29 d. Posttreatment T2-weighted images showed stable signal intensity in all cases, with radiosurgical target site enhancement in 10. All five patients whose images did not show treatment-related enhancement received radiation doses of 35 Gy. The data suggested a correlation between enhancement with radiation dose (P =.06). No correlation of enhancement with treatment response or time to follow-up existed (P >.05). CONCLUSION: The trigeminal nerve often enhances at the target site after radiosurgery. Lack of trigeminal nerve enhancement occurred only with lower doses (35 Gy at 50%). MR imaging may be useful to confirm the presence and location of the treatment site after gamma knife radiosurgery for trigeminal neuralgia.

Focal enhancement of cranial nerve V after radiosurgery with the Leksell gamma knife: experience in 15 patients with medically refractory trigeminal neuralgia. Publishing Authors By Initials

RA Alberico,RA Fenstermaker,J Lobel,

For similar nervous system diseases: cranial nerve diseases: trigeminal nerve diseases: trigeminal neuralgia research abstracts see: nervous system diseases: cranial nerve diseases: trigeminal nerve diseases: trigeminal neuralgia research

PUBMED ID PMID:

MEDLINE DATE:

Focal enhancement of cranial nerve V after radiosurgery with the Leksell gamma knife: experience in 15 patients with medically refractory trigeminal neuralgia. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: AJNR. American journal of neuroradiology

VOLUME: 22

Page Numbers: 1944-8

Journal Abbreviation:

ISSN: 0195-6108

DAY: 14

MONTH: 02

YEAR: 2008

Focal enhancement of cranial nerve V after radiosurgery with the Leksell gamma knife: experience in 15 patients with medically refractory trigeminal neuralgia. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8003708

Focal enhancement of cranial nerve V after radiosurgery with the Leksell gamma knife: experience in 15 patients with medically refractory trigeminal neuralgia. Keywords Mesh Terms:

KEYWORDS: Trigeminal Neuralgia

MESH TERMS: surgery

Chemical & Substance for Abstract: Focal enhancement of cranial nerve V after radiosurgery with the Leksell gamma knife: experience in 15 patients with medically refractory trigeminal neuralgia. Information

Substance Name: Gadolinium DTPA

Registry Number: 80529-93-7

Grant and Affiliation Information for Focal enhancement of cranial nerve V after radiosurgery with the Leksell gamma knife: experience in 15 patients with medically refractory trigeminal neuralgia.

AFFILIATION: Departments of Diagnostic Radiology (R.A.A.) and Neurosurgery (R.A.F., J.L.), Roswell Park Cancer Institute, Buffalo, NY.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: AJNR Am J Neuroradiol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Focal enhancement of cranial nerve V after radiosurgery with the Leksell gamma knife: experience in 15 patients with medically refractory trigeminal neuralgia Related Publications

• Clinical studies with parenteral vitamin A therapy in deafness; preliminary report.
• Demonstration of lysosomal localization for the mammalian ependymin-related protein using classical approaches combined with a novel density shift method.
• Differential Effects of an Adult Observer's Presence on Sex-Typed Play Behavior: A Comparison Between Gender-Schematic and Gender-Aschematic Preschool Children.
• Dipeptidyl-peptidase I does not functionally compensate for the loss of tripeptidyl-peptidase I in the neurodegenerative disease late-infantile neuronal ceroid lipofuscinosis.
• Do mammalian NPC1 and NPC2 play a role in intestinal cholesterol absorption?
• Early endoscopic realignment for complete traumatic rupture of the posterior urethra--21 patients.
• Enhancement of hybridoma formation, clonability and cell proliferation in a nanoparticle-doped aqueous environment.
• Focal enhancement of cranial nerve V after radiosurgery with the Leksell gamma knife: experience in 15 patients with medically refractory trigeminal neuralgia.
• Identification and validation of mannose 6-phosphate glycoproteins in human plasma reveal a wide range of lysosomal and non-lysosomal proteins.
• Minimally invasive transpedicular vertebrectomy for metastatic disease to the thoracic spine.
• Native human autoantibodies targeting GIPC1 identify differential expression in malignant tumors of the breast and ovary.
• Optical fiber immunosensor for the detection of IgG antibody to Rift Valley fever virus in humans.
• Proteomics analysis of serum from mutant mice reveals lysosomal proteins selectively transported by each of the two mannose 6-phosphate receptors.
• Race and gender matter: A multidimensional approach to conceptualizing and measuring stress in African American women.
• Residual levels of tripeptidyl-peptidase I activity dramatically ameliorate disease in late-infantile neuronal ceroid lipofuscinosis.
• The human urine mannose 6-phosphate glycoproteome.
• The mannose 6-phosphate glycoprotein proteome.
• Types, patterns, and predictors of coping with stress during pregnancy: Examination of the Revised Prenatal Coping Inventory in a diverse sample.
• [Consequences of sexually transmissible diseases for male fertility]
• [Conservative treatment of stage III kidney injuries]
• [Lygal zinc paste, a soft paste capable of being removed by washing.]
• [Not Available.]
• [Not Available.]
• [Synchronous bladder metastasis of a clear-cell adenocarcinoma of the kidney]
• [Ureteral reimplantation on psoas bladder: long-term results]