The human neuregulin 1-beta1 (NRG1-beta1, amino acid residues 176-246) was chemically synthesized by Fmoc-based solid phase peptide synthesis (SPPS) followed by folding in a redox buffer. The biological activity of the synthesized NRG1-beta1 was confirmed by ligand-induced tyrosine phosphorylation on Chinese hamster ovary (CHO) cells expressing ErbB-4. Copyright (c) 2007 European Peptide Society and John Wiley & Sons, Ltd.
Fmoc-based solid phase chemical synthesis of 71-meric neuregulin 1-beta1, an epidermal growth factor-like domain. Publishing Authors By Initials
Fmoc-based solid phase chemical synthesis of 71-meric neuregulin 1-beta1, an epidermal growth factor-like domain. Journal Published:
PUBLICATION TYPE: Journal Article
Journal: Journal of peptide science : an official publicati
VOLUME: 14
Page Numbers: 261-6
Journal Abbreviation: J. Pept. Sci.
ISSN: 1075-2617
DAY: 21
MONTH: Mar
YEAR: 2008
Fmoc-based solid phase chemical synthesis of 71-meric neuregulin 1-beta1, an epidermal growth factor-like domain. Information
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LANGUAGE: eng
NlmUniqueID: 9506309
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Grant and Affiliation Information for Fmoc-based solid phase chemical synthesis of 71-meric neuregulin 1-beta1, an epidermal growth factor-like domain.
AFFILIATION: Department of Medicinal Chemistry, Center for Frontier Research in Medicinal Science, 21st Century COE Program, Kyoto Pharmaceutical University, Yamashina-ku, Kyoto 607-8412, Japan.
Country: England
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MEDLINETA: J Pept Sci
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