Fluorescein angiography of anterior uveal melanocytic tumours.

Fluorescein angiography of anterior uveal melanocytic tumours. Research Abstract Details 

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Fluorescein angiography of anterior uveal melanocytic tumours. Abstract Text:

A retrospective analysis of 32 cases of anterior uveal melanocytic tumours included 14 cases in which the tumours could be categorised histologically as malignant, of intermediate cytology with equivocal features of malignancy, or as benign progressive naevi. An additional eight cases without a histological diagnosis were included as benign naevi, because there had been no change in their clinical characteristics after a minimum follow-up of four years. Clinical features and iris fluorescein angiographic (IFA) findings were analysed with respect to these groups in an attempt to identify features predictive of malignant or locally invasive behaviour. Very small tumours were more likely to be benign (p = 0.029). Glaucoma and episcleral vascular dilatation occurred in ciliary body tumours only. Tumours involving the anterior chamber angle proved more likely to be malignant (p = 0.019). IFA showed a disorganised vasculature and gross late leakage in 4/7 (56%) malignant melanomas as well as in 2/6 (33%) tumours with intermediate cytology. No benign tumours showed these features. Four out of nine (44%) benign tumours, but no tumours with malignant or intermediate cytology, showed complete masking of fluorescence. Early leakage of dye from tumour vessels and a geometric tumour vasculature were not specific features of any tumour category. IFA correlated with the cytology and behaviour of anterior uveal melanocytic tumours in 11/22 (50%) of our cases.

Fluorescein angiography of anterior uveal melanocytic tumours. Publishing Authors By Initials

For similar neoplasms: neoplasms by site: eye neoplasms: uveal neoplasms research abstracts see: neoplasms: neoplasms by site: eye neoplasms: uveal neoplasms research

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Fluorescein angiography of anterior uveal melanocytic tumours. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The British journal of ophthalmology

VOLUME: 72

Page Numbers: 326-37

Journal Abbreviation: Br J Ophthalmol

ISSN: 0007-1161

DAY: 28

MONTH: May

YEAR: 1988

Fluorescein angiography of anterior uveal melanocytic tumours. Information

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LANGUAGE: eng

NlmUniqueID: 421041

Fluorescein angiography of anterior uveal melanocytic tumours. Keywords Mesh Terms:

KEYWORDS: Uveal Neoplasms

MESH TERMS: pathology

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Grant and Affiliation Information for Fluorescein angiography of anterior uveal melanocytic tumours.

AFFILIATION: Institute of Ophthalmology, University of London.

Country: ENGLAND

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MEDLINETA: Br J Ophthalmol

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