First synthesis of 3-acetyl-2-aminothiophenes using the Gewald reaction.

First synthesis of 3-acetyl-2-aminothiophenes using the Gewald reaction. Research Abstract Details 

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First synthesis of 3-acetyl-2-aminothiophenes using the Gewald reaction. Abstract Text:

Gernot A Eller,Wolfgang Holzer,Gernot A Eller,Wolfgang Holzer,Gernot A Eller,Wolfgang Holzer,

Novel 3-acetyl-2-aminothiophenes were prepared from cyanoacetone and 1,4-dithianyl-2,5-diols using a modified Gewald reaction. The syntheses of the corresponding acetamides, as well as that of 3-acetyl-2-amino-5-nitrothiophene - an interesting building-block for thiophene azo dyes - are reported. Detailed spectroscopic investigations ((1)H-NMR, (13)C-NMR, MS, IR) of the obtained compounds are presented.

First synthesis of 3-acetyl-2-aminothiophenes using the Gewald reaction. Publishing Authors By Initials

GA Eller,W Holzer,GA Eller,W Holzer,GA Eller,W Holzer,

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First synthesis of 3-acetyl-2-aminothiophenes using the Gewald reaction. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Molecules (Basel, Switzerland)

VOLUME: 11

Page Numbers: 371-6

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ISSN: 1420-3049

DAY: 16

MONTH: 05

YEAR: 2006

First synthesis of 3-acetyl-2-aminothiophenes using the Gewald reaction. Information

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LANGUAGE: eng

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Grant and Affiliation Information for First synthesis of 3-acetyl-2-aminothiophenes using the Gewald reaction.

AFFILIATION: Department of Drug Synthesis, Faculty of Life Sciences, University of Vienna, Austria. gernot.eller@univie.ac.at

Country: Switzerland

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MEDLINETA: Molecules

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