Fibre distribution in the lungs and pleura of subjects with asbestos related diffuse pleural fibrosis.

Fibre distribution in the lungs and pleura of subjects with asbestos related diffuse pleural fibrosis. Research Abstract Details 

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Fibre distribution in the lungs and pleura of subjects with asbestos related diffuse pleural fibrosis. Abstract Text:

The lungs from 13 cases of diffuse pleural fibrosis associated with a history of exposure to asbestos were examined. Samples were taken from the visceral pleura and central and subpleural zones of the lungs for histopathological and mineralogical studies. The fibre type, size, and number were estimated for each of these regions by transmission electron microscopy and energy dispersive x ray analysis. Amphibole fibre counts were raised when compared with a non-occupationally exposed group and matched those seen in cases of pleural plaques, mild asbestosis, and mesothelioma. A wide case to case variation of distribution was seen. No significant difference was apparent between central and subpleural zones, whereas low asbestos counts were found in the pleura; these were mainly short chrysotile fibres. Within the lungs more (45%) of the longer (greater than 4 microns) and thinner (less than 0.25 micron) amphibole fibres were retained in keeping with other studies implicating such fibre profiles in the pathogenesis of asbestos related disease.

Fibre distribution in the lungs and pleura of subjects with asbestos related diffuse pleural fibrosis. Publishing Authors By Initials

For similar respiratory system: pleura research abstracts see: respiratory system: pleura research

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Fibre distribution in the lungs and pleura of subjects with asbestos related diffuse pleural fibrosis. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: British journal of industrial medicine

VOLUME: 48

Page Numbers: 762-70

Journal Abbreviation: Br J Ind Med

ISSN: 0007-1072

DAY: 28

MONTH: Nov

YEAR: 1991

Fibre distribution in the lungs and pleura of subjects with asbestos related diffuse pleural fibrosis. Information

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LANGUAGE: eng

NlmUniqueID: 370637

Fibre distribution in the lungs and pleura of subjects with asbestos related diffuse pleural fibrosis. Keywords Mesh Terms:

KEYWORDS: Pleura

MESH TERMS: pathology

Chemical & Substance for Abstract: Fibre distribution in the lungs and pleura of subjects with asbestos related diffuse pleural fibrosis. Information

Substance Name: Asbestos

Registry Number: 1332-21-4

Grant and Affiliation Information for Fibre distribution in the lungs and pleura of subjects with asbestos related diffuse pleural fibrosis.

AFFILIATION: Department of Pathology, Llandough Hospital, Penarth.

Country: ENGLAND

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MEDLINETA: Br J Ind Med

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