Femtosecond laser versus mechanical microkeratome for LASIK: a randomized controlled study.

Femtosecond laser versus mechanical microkeratome for LASIK: a randomized controlled study. Research Abstract Details 

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Femtosecond laser versus mechanical microkeratome for LASIK: a randomized controlled study. Abstract Text:

Sanjay V Patel,Leo J Maguire,Jay W McLaren,David O Hodge,William M Bourne,

PURPOSE: To compare corneal haze (backscattered light) and visual outcomes between fellow eyes randomized to LASIK with the flap created by a femtosecond laser (bladeless) or with the flap created by a mechanical microkeratome. DESIGN: Randomized, controlled, paired-eye study. PARTICIPANTS: Twenty-one patients (42 eyes) received LASIK for myopia or myopic astigmatism. METHODS: One eye of each patient was randomized to flap creation with a femtosecond laser (IntraLase FS, IntraLase Corp., Irvine, CA) with intended thickness of 120 microm, and the fellow eye to flap creation with a mechanical microkeratome (Hansatome, Bausch & Lomb, Rochester, NY) with intended thickness of 180 microm. Patients were examined before and at 1, 3, and 6 months after LASIK. MAIN OUTCOME MEASURES: Corneal backscatter, high-contrast visual acuity, manifest refractive error, contrast sensitivity, and intraocular forward light scatter were measured at each examination. Flap thickness was measured by confocal microscopy at 1 month, and patients were asked if they preferred the vision in either eye at 3 months. RESULTS: Corneal backscatter was 6% higher after bladeless LASIK than after LASIK with the mechanical microkeratome at 1 month (P = 0.007), but not at 3 or 6 months. High-contrast visual acuity, contrast sensitivity, and forward light scatter did not differ between treatments at any examination. Flap thicknesses at 1 month were 143+/-16 microm (bladeless, mean +/- standard deviation) and 138+/-22 microm (mechanical microkeratome), with no statistical difference in variances. At 3 months, 5 patients preferred the bladeless eye, 7 patients preferred the microkeratome eye, and 9 patients had no preference. CONCLUSIONS: The method of flap creation did not affect visual outcomes during the first 6 months after LASIK. Although corneal backscatter was greater early after bladeless LASIK than LASIK with the mechanical microkeratome, patients did not perceive a difference in vision.

Femtosecond laser versus mechanical microkeratome for LASIK: a randomized controlled study. Publishing Authors By Initials

SV Patel,LJ Maguire,JW McLaren,DO Hodge,WM Bourne,

For similar visual acuity research abstracts see: visual acuity research

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Femtosecond laser versus mechanical microkeratome for LASIK: a randomized controlled study. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Ophthalmology

VOLUME: 114

Page Numbers: 1482-90

Journal Abbreviation: Ophthalmology

ISSN: 1549-4713

DAY: 13

MONTH: 03

YEAR: 2007

Femtosecond laser versus mechanical microkeratome for LASIK: a randomized controlled study. Information

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LANGUAGE: eng

NlmUniqueID: 7802443

Femtosecond laser versus mechanical microkeratome for LASIK: a randomized controlled study. Keywords Mesh Terms:

KEYWORDS: Visual Acuity

MESH TERMS: physiology

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Grant and Affiliation Information for Femtosecond laser versus mechanical microkeratome for LASIK: a randomized controlled study.

AFFILIATION: Department of Ophthalmology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA. patel.sanjay@mayo.edu

Country: United States

AGENCY: United States NEI

GRANT: EY 02037

ACRONYM: EY

MEDLINETA: Ophthalmology

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