Femtosecond laser corneal ablation threshold: dependence on tissue depth and laser pulse width.

Femtosecond laser corneal ablation threshold: dependence on tissue depth and laser pulse width. Research Abstract Details 

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Femtosecond laser corneal ablation threshold: dependence on tissue depth and laser pulse width. Abstract Text:

Hui Sun,Meng Han,Markolf H Niemz,Josef F Bille,Hui Sun,Meng Han,Markolf H Niemz,Josef F Bille,

BACKGROUND AND OBJECTIVE: Diode pumped, all-solid-state ultrafast lasers are now widely used to perform minimally invasive refractive surgery and keratoplasty procedures. Despite such use, a systematic study concerning ultrafast laser-tissue interactions is lacking. We determined the corneal ablation threshold as a function of the laser pulse width and stromal depth by simultaneous monitoring of the intensity of the laser-induced plasma and the second harmonic generation signals (SHG) from the collagen. STUDY DESIGN/MATERIALS AND METHODS: Ablation thresholds in porcine cornea samples were determined using three diode pumped all-solid-state ultrafast lasers (a Nd:glass femtosecond laser, a Yb:KYW femtosecond laser, and a Nd: YAG picosecond laser) over a range from 800 femtoseconds to 20 picoseconds. RESULTS: Corneal ablation threshold remained nearly constant within the first 200 microm of stroma and was consistent with previous findings with the threshold proportional to the square root of the laser pulse width. CONCLUSION: Corneal ablation thresholds can be precisely determined by simultaneous monitoring of the intensity of the laser-induced plasma and the SHG from the cornea.

Femtosecond laser corneal ablation threshold: dependence on tissue depth and laser pulse width. Publishing Authors By Initials

H Sun,M Han,MH Niemz,JF Bille,H Sun,M Han,MH Niemz,JF Bille,

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Femtosecond laser corneal ablation threshold: dependence on tissue depth and laser pulse width. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Lasers in surgery and medicine

VOLUME: 39

Page Numbers: 654-8

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ISSN: 0196-8092

DAY: 27

MONTH: Sep

YEAR: 2007

Femtosecond laser corneal ablation threshold: dependence on tissue depth and laser pulse width. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Femtosecond laser corneal ablation threshold: dependence on tissue depth and laser pulse width.

AFFILIATION: Department of Ophthalmology, University of California, Irvine, California 92697, USA.

Country: United States

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MEDLINETA: Lasers Surg Med

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