Feasibility of multimodality therapy including extended resections in stage IVA thymoma.

Feasibility of multimodality therapy including extended resections in stage IVA thymoma. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Feasibility of multimodality therapy including extended resections in stage IVA thymoma. Abstract Text:

James Huang,Nabil P Rizk,William D Travis,Venkatraman E Seshan,Manjit S Bains,Joseph Dycoco,Robert J Downey,Raja M Flores,Bernard J Park,Valerie W Rusch,

OBJECTIVE: Extended resections for advanced-stage thymomas are not commonly performed because of the potential morbidity in the face of unclear survival or palliative benefit. We reviewed our experience with multimodality treatment for Masaoka stage IVA thymomas for feasibility and outcomes. METHODS: We conducted a retrospective review of a single-institution surgical database. Data included patient demographics, preoperative staging and treatment, perioperative events, pathologic findings, and postoperative outcomes. RESULTS: During the period from 1996 to 2006, 18 patients who had Masaoka stage IVA thymoma underwent surgical resection. All patients received preoperative chemotherapy. Four patients with extensive pleural involvement underwent concomitant extrapleural pneumonectomy and postoperative hemithoracic radiation. Complete resection was achieved in 12 (67%) patients. There was no operative mortality. With a median follow-up of 32.2 months (range 1.4-129.9 months), 3-year, 5-year, and 10-year survivals were 91%, 78%, and 65%, respectively, and median survival has not yet been reached. CONCLUSION: Multimodality therapy including extended surgical resection can be performed in select patients with stage IVA thymoma with low morbidity and mortality and can result in excellent long-term survival.

Feasibility of multimodality therapy including extended resections in stage IVA thymoma. Publishing Authors By Initials

J Huang,NP Rizk,WD Travis,VE Seshan,MS Bains,J Dycoco,RJ Downey,RM Flores,BJ Park,VW Rusch,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Feasibility of multimodality therapy including extended resections in stage IVA thymoma. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The Journal of thoracic and cardiovascular surgery

VOLUME: 134

Page Numbers: 1477-83; discussion 1483-4

Journal Abbreviation: J. Thorac. Cardiovasc. Surg.

ISSN: 1097-685X

DAY: 26

MONTH: 10

YEAR: 2007

Feasibility of multimodality therapy including extended resections in stage IVA thymoma. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 376343

Feasibility of multimodality therapy including extended resections in stage IVA thymoma. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Feasibility of multimodality therapy including extended resections in stage IVA thymoma. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Feasibility of multimodality therapy including extended resections in stage IVA thymoma.

AFFILIATION: Thoracic Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: J Thorac Cardiovasc Surg

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Feasibility of multimodality therapy including extended resections in stage IVA thymoma Related Publications

• Atlanto-axial arthrodesis.
• DNA damage and repair capacity in patients with lung cancer: prediction of multiple primary tumors.
• Design and implementation of a continuous microwave heating system for ballast water treatment.
• Disrupting calcium channel expression to lower blood pressure: new targeting of a well-known channel.
• Extrapleural pneumonectomy versus pleurectomy/decortication in the surgical management of malignant pleural mesothelioma: Results in 663 patients.
• Feasibility of multimodality therapy including extended resections in stage IVA thymoma.
• Induction chemotherapy, extrapleural pneumonectomy, and postoperative high-dose radiotherapy for locally advanced malignant pleural mesothelioma: a phase II trial.
• Multimodality therapy for locally advanced thymomas: state of the art or investigational therapy?
• Oxime silanes: structure/toxicity relationships.
• Some physiological effects associated with chronic caloric restriction.
• Starring TREK-1: the next generation of vascular K+ channels.
• The carcinogenicity of compounds related to 2-acetylaminofluorene. III. Aminobiphenyl and benzidine derivatives.
• The carcinogenicity of compounds related to 2-acetylaminofluorene. II. Variations in the bridges and the 2-substituent.
• The impact of lymph node station on survival in 348 patients with surgically resected malignant pleural mesothelioma: implications for revision of the American Joint Committee on Cancer staging system.
• The influence of peers on risky sexual behaviour during adolescence.
• The synergistic action of mixtures of certain hepatic carcinogens.
• Use of video-assisted thoracic surgery for lobectomy in the elderly results in fewer complications.
• [A contribution to the problem of angina pectoris electrica.]
• [The Myerson-Dura-Bland acrylic resin shell]
• [The law of maintenance of the living substance.]
• [The law of maintenance of the living substance.]
• [Use of lispamol in obstetrics.]