Fatal dextropropoxyphene poisonings in Jutland, Denmark.

Fatal dextropropoxyphene poisonings in Jutland, Denmark. Research Abstract Details 

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Fatal dextropropoxyphene poisonings in Jutland, Denmark. Abstract Text:

E Kaa,J B Dalgaard,

For many years dextropropoxyphene (dxp) has been the medicament most frequently occurring in drug poisoning cases examined at the Institute of Forensic Medicine, University of Aarhus. This study includes 85 cases of acute fatal poisoning examined in the period 1985-1987 in which dxp alone (40 cases) or in combination with alcohol (29 cases) and/or other drugs (16 cases) contributed significantly to death. Two-thirds of the deceased were men and one-third women. The average age was 37 years for both sexes. More than half of the deceased were drug and/or alcohol misusers. Eighteen were drug addicts. Half of the deaths resulted from accidents, while 40% were suicides. Accidental deaths prevailed among younger men. In a majority of the cases the drug had been taken orally. In these cases the median total blood concentration of dxp and the metabolite nordextropropoxyphene (ndxp) was 17 mg/kg in the suicide cases and 7.1 mg/kg in the accident cases. The corresponding figures for dxp without metabolite were 9.4 mg/kg and 2.2 mg/kg, respectively. The median value of the quotient dxp/ndxp was 1.9 in the suicide cases and 0.5 in the accident cases. The quotient, together with the concentrations of the drug, may therefore indicate the manner of death in many cases.

Fatal dextropropoxyphene poisonings in Jutland, Denmark. Publishing Authors By Initials

E Kaa,JB Dalgaard,

For similar behavior and behavior mechanisms: behavior: behavioral symptoms: self-injurious behavior: suicide research abstracts see: behavior and behavior mechanisms: behavior: behavioral symptoms: self-injurious behavior: suicide research

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Fatal dextropropoxyphene poisonings in Jutland, Denmark. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Zeitschrift für Rechtsmedizin. Journal of legal me

VOLUME: 102

Page Numbers: 107-15

Journal Abbreviation: Z. Rechtsmed.

ISSN: 0044-3433

DAY: 20

MONTH: 02

YEAR: 1989

Fatal dextropropoxyphene poisonings in Jutland, Denmark. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 247437

Fatal dextropropoxyphene poisonings in Jutland, Denmark. Keywords Mesh Terms:

KEYWORDS: Suicide

MESH TERMS: epidemiology

Chemical & Substance for Abstract: Fatal dextropropoxyphene poisonings in Jutland, Denmark. Information

Substance Name: Dextropropoxyphene

Registry Number: 469-62-5

Grant and Affiliation Information for Fatal dextropropoxyphene poisonings in Jutland, Denmark.

AFFILIATION: Department of Forensic Chemistry, University of Aarhus, Denmark.

Country: GERMANY, WEST

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MEDLINETA: Z Rechtsmed

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