Factors determining early left atrial reverse remodeling after mitral valve surgery.

Factors determining early left atrial reverse remodeling after mitral valve surgery. Research Abstract Details 

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Factors determining early left atrial reverse remodeling after mitral valve surgery. Abstract Text:

Deok-Kyu Cho,Jong-Won Ha,Byung-Chul Chang,Se-Hwa Lee,Se-Jung Yoon,Chi Young Shim,Jung Rae Cho,Jung-Sun Kim,Eui-Young Choi,Se-Joong Rim,Namsik Chung,Deok-Kyu Cho,Jong-Won Ha,Byung-Chul Chang,Se-Hwa Lee,Se-Jung Yoon,Chi Young Shim,Jung Rae Cho,Jung-Sun Kim,Eui-Young Choi,Se-Joong Rim,Namsik Chung,

This study aimed to investigate the factors determining early left atrial (LA) reverse remodeling after mitral valve (MV) surgery. The left atrium is frequently dilated in patients with mitral stenosis (MS) or mitral regurgitation (MR). MV surgery usually results in LA volume reduction. However, the factors associated with LA reverse remodeling after MV surgery are not clearly defined. One hundred thirty-eight patients (51 men, 87 women; mean age, 53 years) underwent transthoracic echocardiography before and after MV surgery. Maximal LA volume was measured using the prolate ellipsoid model. The percentage of LA volume change was calculated. The patients were grouped according to age (<50 vs >/=50 years), predominant lesion (pure MR vs some degree of MS), type of surgery (MV repair vs MV replacement), and preoperative rhythm (sinus rhythm vs atrial fibrillation). LA volume decreased from 147 +/- 93 to 103 +/- 43 ml (p <0.001) after surgery. LA reverse remodeling was more prominent in patients who were <50 years old (percentage of LA volume change -31.2 +/- 17.4 vs -18.4 +/- 19.2, p <0.001), had pure MR (percentage of LA volume change -30.4 +/- 18.6 vs -17.3 +/- 18.2, p <0.001), and had a preoperative sinus rhythm (percentage of LA volume change -28.5 +/- 17.7 vs -20.5 +/- 20.0, p = 0.019). In conclusion, on stepwise multiple regression analysis, preoperative LA volume, predominant lesion, age, and cardiac rhythm were significant predictors of LA reverse remodeling. A larger preoperative LA volume, MR rather than MS, younger age at the time of surgery, and sinus rhythm were important predictors of LA reverse remodeling after MV surgery.

Factors determining early left atrial reverse remodeling after mitral valve surgery. Publishing Authors By Initials

DK Cho,JW Ha,BC Chang,SH Lee,SJ Yoon,CY Shim,JR Cho,JS Kim,EY Choi,SJ Rim,N Chung,DK Cho,JW Ha,BC Chang,SH Lee,SJ Yoon,CY Shim,JR Cho,JS Kim,EY Choi,SJ Rim,N Chung,

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Factors determining early left atrial reverse remodeling after mitral valve surgery. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The American journal of cardiology

VOLUME: 101

Page Numbers: 374-7

Journal Abbreviation: Am. J. Cardiol.

ISSN: 0002-9149

DAY: 1

MONTH: Feb

YEAR: 2008

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LANGUAGE: eng

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Grant and Affiliation Information for Factors determining early left atrial reverse remodeling after mitral valve surgery.

AFFILIATION: Division of Cardiology, Yonsei Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, South Korea.

Country: United States

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MEDLINETA: Am J Cardiol

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