Factors associated with nonmedical use of prescription opioids among heroin-abusing research volunteers.

Factors associated with nonmedical use of prescription opioids among heroin-abusing research volunteers. Research Abstract Details 

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Factors associated with nonmedical use of prescription opioids among heroin-abusing research volunteers. Abstract Text:

Caren L Steinmiller,Mark Greenwald,Caren L Steinmiller,Mark Greenwald,Caren L Steinmiller,Mark Greenwald,

This retrospective study examined factors associated with nonmedical opioid use among 208 heroin-abusing research volunteers in the metropolitan Detroit area. Drug and medical history data were obtained from structured questionnaires administered during screening for behavioral pharmacology research studies. Analyses included demographic data (gender and race), history of drug use (prescribed, nonmedical, and route of use), and potentially relevant medical conditions (e.g., pain). All volunteers (mean age=43 years) reported chronic heroin use (mean duration=21 years), with 66% currently injecting heroin. Two multiple logistic regression analyses were used to identify factors related to lifetime and current nonmedical opioid use (predicted variables). Odds ratios (ORs) from logistic regression--which predicted membership in lifetime heroin use only (n=52) versus heroin plus nonmedical opioid use (n=156) groups--indicated that nonmedical opioid use was significantly associated with legitimate prescription opioid use (OR=10.5), having ever sought treatment for heroin use (OR=4.21), and a history of lung problems (OR=3.66) and dental pain (OR=2.58). The finding of a significant positive association (R(2)=.83) between lifetime rates of medical and nonmedical use of specific opioids in this study is consistent with previous observations that prescription opioid use or availability is a prominent risk factor for nonmedical opioid use. A limitation of this study is that age-of-onset data were not originally collected; thus, the relative (predictive) order of pain conditions, medical use, and nonmedical use of opioids cannot be determined retrospectively.

Factors associated with nonmedical use of prescription opioids among heroin-abusing research volunteers. Publishing Authors By Initials

CL Steinmiller,M Greenwald,CL Steinmiller,M Greenwald,CL Steinmiller,M Greenwald,

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Factors associated with nonmedical use of prescription opioids among heroin-abusing research volunteers. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Experimental and clinical psychopharmacology

VOLUME: 15

Page Numbers: 492-500

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ISSN: 1064-1297

DAY: 10

MONTH: Oct

YEAR: 2007

Factors associated with nonmedical use of prescription opioids among heroin-abusing research volunteers. Information

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LANGUAGE: eng

NlmUniqueID: 9419066

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Chemical & Substance for Abstract: Factors associated with nonmedical use of prescription opioids among heroin-abusing research volunteers. Information

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Grant and Affiliation Information for Factors associated with nonmedical use of prescription opioids among heroin-abusing research volunteers.

AFFILIATION: Department of Psychiatry and Behavioral Neurosciences, Substance Abuse Research Division, Wayne State University, Detroit, Michigan 48207, USA. csteinmi@med.wayne.edu

Country: United States

AGENCY: United States NIDA

GRANT: T32 DA07310

ACRONYM: DA

MEDLINETA: Exp Clin Psychopharmacol

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