Extensively drug-resistant tuberculosis: new strains, new challenges.

Extensively drug-resistant tuberculosis: new strains, new challenges. Research Abstract Details 

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Extensively drug-resistant tuberculosis: new strains, new challenges. Abstract Text:

Extensively drug-resistant (XDR)-TB, defined as TB with resistance to at least isoniazid, rifampin, a fluoroquinolone and either amikacin, kanamycin or capreomycin, is a stark setback for global TB control. Overburdened public-health systems with inadequate resources for case detection and management and high HIV coinfection rates in many regions have contributed to the emergence of XDR-TB. Patients with XDR-TB have poor outcomes, prolonged infectious periods and limited treatment options. To prevent an epidemic of untreatable XDR-TB, improvements in XDR-TB surveillance, increased laboratory capacity for rapid detection of drug-resistant strains, better infection control and the development of new therapeutics are urgently needed.

Extensively drug-resistant tuberculosis: new strains, new challenges. Publishing Authors By Initials

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Extensively drug-resistant tuberculosis: new strains, new challenges. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Expert review of anti-infective therapy

VOLUME: 6

Page Numbers: 713-24

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ISSN: 1744-8336

DAY: 13

MONTH: Oct

YEAR: 2008

Extensively drug-resistant tuberculosis: new strains, new challenges. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Extensively drug-resistant tuberculosis: new strains, new challenges.

AFFILIATION: Division of Infectious Disease, Department of Pediatrics, University of California San Francisco, San Francisco, CA 94143-0136, USA. banerjeer@peds.ucsf.edu

Country: England

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MEDLINETA: Expert Rev Anti Infect Ther

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