Expression of toll-like receptor 2 and 4 in dental pulp.

Expression of toll-like receptor 2 and 4 in dental pulp. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Expression of toll-like receptor 2 and 4 in dental pulp. Abstract Text:

Noriko Mutoh,Nobuyuki Tani-Ishii,Keiichi Tsukinoki,Keiko Chieda,Kiyoko Watanabe,Noriko Mutoh,Nobuyuki Tani-Ishii,Keiichi Tsukinoki,Keiko Chieda,Kiyoko Watanabe,

Toll-like receptors (TLRs) are important factors in innate immune responses because they mediate signals from bacterial cell wall components during inflammatory reactions. However, the role of TLR in dental pulp, which is bounded by hard tissues, is little understood. The present study investigated the expression of TLR-2 and TLR-4 in experimentally inflamed pulp by quantitative real-time polymerase chain reaction and immunohistochemistry. Total RNA isolated from pulp tissue from 0 to 72 hours after bacterial dentinal infection. The TLR-2 messenger RNA (mRNA) level was 30-fold higher than the TLR-4 mRNA level at 9 hours. The TLR-2 mRNA level in pulp began to increase by 3 hours after bacterial infection, reaching a maximum level after 9 hours and gradually decreasing from 9 to 72 hours. Numerous TLR-2- and CD64-positive cells detected on macrophage and dendritic-like cells, TLR-4-positive cells detected a little in the pulp at 9 hours. These results suggest that TLR-2 may be mainly regulated during the early stage of pulp inflammation triggered by bacterial infection.

Expression of toll-like receptor 2 and 4 in dental pulp. Publishing Authors By Initials

N Mutoh,N Tani-Ishii,K Tsukinoki,K Chieda,K Watanabe,N Mutoh,N Tani-Ishii,K Tsukinoki,K Chieda,K Watanabe,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Expression of toll-like receptor 2 and 4 in dental pulp. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of endodontics

VOLUME: 33

Page Numbers: 1183-6

Journal Abbreviation:

ISSN: 0099-2399

DAY: 26

MONTH: 07

YEAR: 2007

Expression of toll-like receptor 2 and 4 in dental pulp. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7511484

Expression of toll-like receptor 2 and 4 in dental pulp. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Expression of toll-like receptor 2 and 4 in dental pulp. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Expression of toll-like receptor 2 and 4 in dental pulp.

AFFILIATION: Department of Maxillofacial Diagnostic Science, Division of Pathology, Kanagawa Dental College, Kanagawa, Japan.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: J Endod

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Expression of toll-like receptor 2 and 4 in dental pulp Related Publications

• Analysis of the CC chemokine receptor 5 delta32 polymorphism in a Brazilian population with cutaneous leishmaniasis.
• Behavioral Determination of Odor Preference is Coded by the Oscillation Frequency in a Collective Oscillating Network of a Terrestrial Mollusk.
• Cost-effectiveness of radiofrequency ablation and surgical therapy for small hepatocellular carcinoma of 3cm or less in diameter.
• Decreased renal expressions of heat shock protein-72 and -25 are associated with renal dysfunction in biliary cirrhotic rats.
• Design of a synchrotron radiation source at Tohoku University.
• Divergent activities of interferon-alpha subtypes against intracellular hepatitis C virus replication.
• Effect of the moderate exercise on performance in upper/lower limb during long term bed rest.
• Effects of aminoglutethimide phosphate on litter size and birth weight in superovulated rats.
• Efficacy of ecabet sodium enema on steroid resistant or steroid dependent ulcerative colitis.
• Efficient Gene Transfer into Differentiated Human Trophoblast Cells with Adenovirus Vector Containing RGD Motif in the Fiber Protein.
• Enhancement of cytoprotective ability and cell restoration in 70-kDa heat shock protein gene-transfected rat gastric mucosal cells.
• Epimorphin expression and stellate cell status in mouse liver injury.
• Establishment of a novel chondrocytic cell line N1511 derived from p53-null mice.
• Genipin prevents fulminant hepatic failure resulting in reduction of lethality through the suppression of TNF-alpha production.
• Heart rate turbulence slope reduction in imminent ventricular tachyarrhythmia and its implications.
• Hepatic gene expression in hepatocyte-specific Pten deficient mice showing steatohepatitis without ethanol challenge.
• High-performance EUV/soft X-ray ellipsometry system using multilayer mirrors.
• Hydrodynamics-based gene delivery of naked DNA encoding fetal liver kinase-1 gene effectively suppresses the growth of pre-existing tumors.
• Mucins and ocular surface disease.
• Optical design for a bending-magnet beamline based on a varied-line-spacing plane grating.
• Proline promoted synthesis of ring-fused homodimers: self-condensation of alpha,beta-unsaturated aldehydes.
• Pyocyanin isolated from a marine microbial population: synergistic production between two distinct bacterial species and mode of action.
• Root caries prevalence in a group of Brazilian adult dental patients.
• Scrotal imaging.
• Synthesis and biological activity of 5',9-anhydro-3-purine-isonucleosides as potential anti-hepatitis C virus agents.
• Technical note: measurement of ferritin in bovine milk and its clinical significance.
• Transmission multilayer polarizers for use in the 55-90 eV region.
• Treatment for intercostal arterial aneurysm in neurofibromatosis type 1.
• Two cases requiring external reinforcement in perceptual learning.
• Well-differentiated adenocarcinoma mimicking complete-type intestinal metaplasia in the stomach.