Expression of MUC1 and MUC2 glycoproteins in laryngeal cancer.

Expression of MUC1 and MUC2 glycoproteins in laryngeal cancer. Research Abstract Details 

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Expression of MUC1 and MUC2 glycoproteins in laryngeal cancer. Abstract Text:

J P Jeannon,V Aston,F W Stafford,J V Soames,J A Wilson,

The aim of this study was to examine the expression of MUC1 and MUC2 glycoproteins in laryngeal cancer and to determine if mucin expression is related to prognosis. The study included laryngeal specimens from 57 patients comprising of 36 laryngeal carcinomas and 21 normal controls. High MUC1 expression was found in both carcinomas and normal control groups (P = 0.689, Fisher's exact test). High levels of MUC2 expression were only detected in carcinomas versus controls (P = 0.009, Fisher's exact test). Using multivariate analysis neither MUC1 nor MUC2 expression significantly related to survival. MUC1 expression however, did correlate with T stage. Advanced T stage was associated with prognosis (P = 0.001).

Expression of MUC1 and MUC2 glycoproteins in laryngeal cancer. Publishing Authors By Initials

JP Jeannon,V Aston,FW Stafford,JV Soames,JA Wilson,

For similar biological factors: biological markers: tumor markers, biological research abstracts see: biological factors: biological markers: tumor markers, biological research

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Expression of MUC1 and MUC2 glycoproteins in laryngeal cancer. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Clinical otolaryngology and allied sciences

VOLUME: 26

Page Numbers: 109-12

Journal Abbreviation:

ISSN: 0307-7772

DAY: 30

MONTH: Apr

YEAR: 2001

Expression of MUC1 and MUC2 glycoproteins in laryngeal cancer. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7701793

Expression of MUC1 and MUC2 glycoproteins in laryngeal cancer. Keywords Mesh Terms:

KEYWORDS: Tumor Markers, Biological

MESH TERMS: pathology

Chemical & Substance for Abstract: Expression of MUC1 and MUC2 glycoproteins in laryngeal cancer. Information

Substance Name: Tumor Markers, Biological

Registry Number: 0

Grant and Affiliation Information for Expression of MUC1 and MUC2 glycoproteins in laryngeal cancer.

AFFILIATION: Department of Otolaryngology/Head and Neck Surgery, University of Newcastle-upon-Tyne, UK.

Country: England

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MEDLINETA: Clin Otolaryngol Allied Sci

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