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Expression of CD40 and CD40L on peripheral blood mononuclear cells in patients with condyloma acuminatum.

Expression of CD40 and CD40L on peripheral blood mononuclear cells in patients with condyloma acuminatum. Research Abstract Details 

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  • Expression of CD40 and CD40L on peripheral blood mononuclear cells in patients with condyloma acuminatum. Abstract Text:

    dongxian liuDongxian Liu,wen jiangWen Jiang,xingping chenXingping Chen,yingling chenYingling Chen,dongliang yangDongliang Yang,

    To observe the expression of CD40/CD40L on peripheral blood mononuclear cells (PBMC) in patients with condyloma acuminatum (CA), flow cytometry was employed to examine the expression of CD40 and CD40L on PMBC in 36 patients with CA and 20 healthy controls. Our results showed that mean level of CD40 expression in CA patients was significantly lower than that in the controls (6.58% +/- 2.74% vs 14.81% +/- 6.12%, t = 5.703, P < 0.05); the average level of CD40L in CA patients was also significantly lower than that in the controls (0.73% +/- 0.54% vs 2.67% +/- 2.43%, t = 3.532, P < 0.05). Our results suggest that the reduced costimulatory interaction of CD40 and CD40L in CA patients may be one of the important factors responsible for the low cellular immunity.

    Expression of CD40 and CD40L on peripheral blood mononuclear cells in patients with condyloma acuminatum. Publishing Authors By Initials

    d liuD Liu,w jiangW Jiang,x chenX Chen,y chenY Chen,d yangD Yang,

    For similar abstracts research abstracts see: abstracts research

    PUBMED ID PMID:

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    Expression of CD40 and CD40L on peripheral blood mononuclear cells in patients with condyloma acuminatum. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Journal of Huazhong University of Science and Tech

    VOLUME: 26

    Page Numbers: 378-9

    Journal Abbreviation:

    ISSN: 1672-0733

    DAY: 11

    MONTH: 09

    YEAR: 2006

    Expression of CD40 and CD40L on peripheral blood mononuclear cells in patients with condyloma acuminatum. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 101169627

    Expression of CD40 and CD40L on peripheral blood mononuclear cells in patients with condyloma acuminatum. Keywords Mesh Terms:

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    Grant and Affiliation Information for Expression of CD40 and CD40L on peripheral blood mononuclear cells in patients with condyloma acuminatum.

    AFFILIATION: Department of Dermatology, Tongji Hospital Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.

    Country: China

    China Research PublicationChina Research Publication

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    MEDLINETA: J Huazhong Univ Sci Technolog

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