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Expression of beta-catenin in developing auditory epithelia of mice.

Expression of beta-catenin in developing auditory epithelia of mice. Research Abstract Details 

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  • Expression of beta-catenin in developing auditory epithelia of mice. Abstract Text:

    shinji takebayashiShinji Takebayashi,takayuki nakagawaTakayuki Nakagawa,ken kojimaKen Kojima,tae-soo kimTae-Soo Kim,tomoko kitaTomoko Kita,youyi dongYouyi Dong,tsuyoshi endoTsuyoshi Endo,fukuichiro iguchiFukuichiro Iguchi,yasushi naitoYasushi Naito,koichi omoriKoichi Omori,juichi itoJuichi Ito,

    This study investigated the role of beta-catenin in the development of mouse auditory epithelia. Inner ears obtained from embryonic and newborn mice were used. Expression of beta-catenin was examined together with the expression of Ki-67, a marker for proliferating cells, or myosin VIIa, a marker for differentiated hair cells. In the early phase of development, intense expression of beta-catenin was found in auditory epithelia in which a number of Ki-67-positive cells were identified. Together with a decrease in proliferating cells, the intensity and area of beta-catenin expression were reduced. In addition, during differentiation and maturation of hair cells, the area of beta-catenin expression was further limited. These findings suggest that patterns of expression of beta-catenin are closely linked with the status of auditory epithelia development.

    Expression of beta-catenin in developing auditory epithelia of mice. Publishing Authors By Initials

    s takebayashiS Takebayashi,t nakagawaT Nakagawa,k kojimaK Kojima,ts kimTS Kim,t kitaT Kita,y dongY Dong,t endoT Endo,f iguchiF Iguchi,y naitoY Naito,k omoriK Omori,j itoJ Ito,

    For similar proteins: armadillo domain proteins: beta catenin research abstracts see: proteins: armadillo domain proteins: beta catenin research

    PUBMED ID PMID:

    MEDLINE DATE:

    Expression of beta-catenin in developing auditory epithelia of mice. Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: Acta oto-laryngologica. Supplementum

    VOLUME:

    Page Numbers: 18-21

    Journal Abbreviation:

    ISSN: 0365-5237

    DAY: 13

    MONTH: Mar

    YEAR: 2004

    Expression of beta-catenin in developing auditory epithelia of mice. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 370355

    Expression of beta-catenin in developing auditory epithelia of mice. Keywords Mesh Terms:

    KEYWORDS: beta Catenin

    MESH TERMS: physiology

    Chemical & Substance for Abstract: Expression of beta-catenin in developing auditory epithelia of mice. Information

    Substance Name: Dynein ATPase

    Registry Number: EC 3.6.4.2

    Grant and Affiliation Information for Expression of beta-catenin in developing auditory epithelia of mice.

    AFFILIATION: Department of Otolaryngology--Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

    Country: Norway

    Norway Research PublicationNorway Research Publication

    AGENCY:

    GRANT:

    ACRONYM:

    MEDLINETA: Acta Otolaryngol Suppl

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