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Expression of antimicrobial peptide genes encoding Enbocin and Gloverin isoforms in the silkworm, Bombyx mori.

Expression of antimicrobial peptide genes encoding Enbocin and Gloverin isoforms in the silkworm, Bombyx mori. Research Abstract Details 

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  • Expression of antimicrobial peptide genes encoding Enbocin and Gloverin isoforms in the silkworm, Bombyx mori. Abstract Text:

    yoichi kanekoYoichi Kaneko,seiichi furukawaSeiichi Furukawa,hiromitsu tanakaHiromitsu Tanaka,minoru yamakawaMinoru Yamakawa,yoichi kanekoYoichi Kaneko,seiichi furukawaSeiichi Furukawa,hiromitsu tanakaHiromitsu Tanaka,minoru yamakawaMinoru Yamakawa,

    Antimicrobial peptides, Enbocin and Gloverin isoforms from the silkworm Bombyx mori, were analyzed for expression of these peptide genes. Tissue-specific expression of Enbocin and Bmgloverin isoform genes was observed mainly in the fat body upon injection of Escherichia coli. Peptidoglycan and lipopolysaccharide triggered expression of these genes in vivo. On the other hand, lipid A activated Bmgloverin isoform genes but not Enbocin isoform genes. These results illustrate the fact that expression of Enbocin and Bmgloverin isoform genes is inducible by bacteria and that the effects of bacterial cell wall components on the activation of these peptide genes are not necessarily the same. In addition, selective activation of the Enbocin2, Bmgloverin2, and Bmgloverin4 genes by BmRelB rather than BmRelA was observed, providing additional evidence for the occurrence of selective activation of antimicrobial peptide genes by a Rel protein. These results suggest complex regulatory mechanisms in insect antimicrobial peptide genes by bacterial cell wall components.

    Expression of antimicrobial peptide genes encoding Enbocin and Gloverin isoforms in the silkworm, Bombyx mori. Publishing Authors By Initials

    y kanekoY Kaneko,s furukawaS Furukawa,h tanakaH Tanaka,m yamakawaM Yamakawa,y kanekoY Kaneko,s furukawaS Furukawa,h tanakaH Tanaka,m yamakawaM Yamakawa,

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    Expression of antimicrobial peptide genes encoding Enbocin and Gloverin isoforms in the silkworm, Bombyx mori. Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: Bioscience, biotechnology, and biochemistry

    VOLUME: 71

    Page Numbers: 2233-41

    Journal Abbreviation: Biosci. Biotechnol. Biochem.

    ISSN: 0916-8451

    DAY: 7

    MONTH: 09

    YEAR: 2007

    Expression of antimicrobial peptide genes encoding Enbocin and Gloverin isoforms in the silkworm, Bombyx mori. Information

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    LANGUAGE: eng

    NlmUniqueID: 9205717

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    Grant and Affiliation Information for Expression of antimicrobial peptide genes encoding Enbocin and Gloverin isoforms in the silkworm, Bombyx mori.

    AFFILIATION: Graduate School of Life and Enviromental Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8572, Japan.

    Country: Japan

    Japan Research PublicationJapan Research Publication

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    MEDLINETA: Biosci Biotechnol Biochem

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