Exposure to vinyl chloride monomer: report on a cohort study.

Exposure to vinyl chloride monomer: report on a cohort study. Research Abstract Details 

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Exposure to vinyl chloride monomer: report on a cohort study. Abstract Text:

In 1980 a prospective exposed/non-exposed cohort study was initiated in France by the Institut National de la Santé et de la Recherche Médicale (INSERM U 287) to evaluate the association between mortality and cancer morbidity and occupational exposure to vinyl chloride monomer (VCM). Eleven hundred VCM exposed subjects and 1100 VCM non-exposed controls matched for age (+/- 2 years), plant, and physician were included and followed up over a five year period for vital, health, and occupational status. The percentages of deaths observed among the exposed (1.8%) and non-exposed subjects (1.6%) did not differ. Eighteen (1.6%) and 15 (1.4%) cases of cancer were reported among exposed and non-exposed subjects, respectively (NS). One case of angiosarcoma of the liver occurred among the exposed group; six cases of lung cancer occurred among exposed subjects and two among non-exposed subjects (NS). The percentage of diseases of the circulatory system was higher (p less than 0.02) in the exposed group than in the non-exposed group: this difference was explained mainly by the high incidence of Raynaud's disease (p less than 0.006). The percentages of diseases of the respiratory system did not differ between the two groups.

Exposure to vinyl chloride monomer: report on a cohort study. Publishing Authors By Initials

For similar cardiovascular diseases: vascular diseases research abstracts see: cardiovascular diseases: vascular diseases research

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Exposure to vinyl chloride monomer: report on a cohort study. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: British journal of industrial medicine

VOLUME: 44

Page Numbers: 711-5

Journal Abbreviation: Br J Ind Med

ISSN: 0007-1072

DAY: 28

MONTH: Oct

YEAR: 1987

Exposure to vinyl chloride monomer: report on a cohort study. Information

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LANGUAGE: eng

NlmUniqueID: 370637

Exposure to vinyl chloride monomer: report on a cohort study. Keywords Mesh Terms:

KEYWORDS: Vascular Diseases

MESH TERMS: chemically induced

Chemical & Substance for Abstract: Exposure to vinyl chloride monomer: report on a cohort study. Information

Substance Name: Polyvinyl Chloride

Registry Number: 9002-86-2

Grant and Affiliation Information for Exposure to vinyl chloride monomer: report on a cohort study.

AFFILIATION: Département de Statistique Médicale, Institut Gustave Roussy, Villejuif, France.

Country: ENGLAND

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MEDLINETA: Br J Ind Med

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