[Experimental study on the myogenic differentiation of marrow mesenchymal stem cells in the local muscle tissues]

[Experimental study on the myogenic differentiation of marrow mesenchymal stem cells in the local muscle tissues] Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

[Experimental study on the myogenic differentiation of marrow mesenchymal stem cells in the local muscle tissues] Abstract Text:

Jing Wang,Chengji Luo,Hui Xu,Xinze Ran,Guohe Yan,Yongping Su,Tianmin Cheng,

OBJECTIVE: To investigate the myogenic differentiation of mesenchymal stem cells (MSCs) after being transplanted into the local muscle tissues. METHODS: The serious muscle-injured model was established by the way of radiation injury, incising, and freezing injury in 36 mouses. Purified MSCs derived from bone marrow of male mouse and MSCs induced by 5-azacytidine (5-Aza-CR) were transplanted into the local of normal muscle tissues and injured muscle tissues of femal mouse. The quantity of MSCs and the myogenic differentiation of implanted MSCs were detected by the method of double labeling, which included fluorescence in situ DNA hybridization (FISH) and immunohistochemistry on the 1st, 3rd, 6th, 9th, 12th, and 15th day after transplantation. RESULTS: The quantity of implanted MSCs decreased as time passed. MSCs' differentiation into myoblasts and positive expression of desmin were observed on the 15th day in purified MSCs group and on the 6th day in induced MSCs groups. CONCLUSION: MSCs could differentiate into myoblasts after being implanted into the local of muscle tissues. The differentiation occurs earlier in the induced MSCs group than that in purified MSCs group.

[Experimental study on the myogenic differentiation of marrow mesenchymal stem cells in the local muscle tissues] Publishing Authors By Initials

J Wang,C Luo,H Xu,X Ran,G Yan,Y Su,T Cheng,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

[Experimental study on the myogenic differentiation of marrow mesenchymal stem cells in the local muscle tissues] Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Zhongguo xiu fu chong jian wai ke za zhi = Zhonggu

VOLUME: 19

Page Numbers: 70-3

Journal Abbreviation:

ISSN: 1002-1892

DAY: 11

MONTH: Jan

YEAR: 2005

[Experimental study on the myogenic differentiation of marrow mesenchymal stem cells in the local muscle tissues] Information

Number of References:

LANGUAGE: chi

NlmUniqueID: 9425194

[Experimental study on the myogenic differentiation of marrow mesenchymal stem cells in the local muscle tissues] Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: [Experimental study on the myogenic differentiation of marrow mesenchymal stem cells in the local muscle tissues] Information

Substance Name:

Registry Number:

Grant and Affiliation Information for [Experimental study on the myogenic differentiation of marrow mesenchymal stem cells in the local muscle tissues]

AFFILIATION: Institute of Combined Injury of PLA, Third Military Medical University, Chongqing 400038, P R China. wangj5768@yahoo.com.cn

Country: China

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Zhongguo Xiu Fu Chong Jian Wai

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Experimental study on the myogenic differentiation of marrow mesenchymal stem cells in the local muscle tissues Related Publications

• Alphavbeta integrins play an essential role in BMP-2 induction of osteoblast differentiation.
• Ethnic differences in incidence of diseases and response to medicines.
• Neurological improvement after cranioplasty - analysis by transcranial doppler ultrasonography.
• Parallel approach for solution-phase synthesis of 2-quinoxalinol analogues and their inhibition of LPS-induced TNF-alpha release on mouse macrophages in vitro.
• Regulation of bone matrix protein expression and induction of differentiation of human osteoblasts and human bone marrow stromal cells by bone morphogenetic protein-2.
• Signal transductions induced by bone morphogenetic protein-2 and transforming growth factor-beta in normal human osteoblastic cells.
• [A new approach to the fast measurement of content of amino acids in Cordyceps sinensis by ANN-NIR]
• [A strain of A/PR/8/34 (H1N1)-like virus isolated from men]
• [An overview of injectable and absorbable gelling scaffolds]
• [Analysis of single cells by capillary electrophoresis]
• [Application of biodegradable polyhydroxybutyrate in medicine and tissue engineering]
• [Bioartificial liver support system: state of the art]
• [Changes in voltage-dependent calcium channel currents of vascular smooth muscle cells isolated from small mesenteric arteries of simulated weightless rats.]
• [Determination of docosyl ferulate in extract of Pygeum africanton Hook. by high performance liquid chromatography (HPLC)]
• [Determination of mercury and selenium in bone by atomic absorption spectrometry after microwave digestion]
• [Determination of potassium, calcium, manganese, chromium and cadmium in 10 kinds of (tobacco) cigarettes by flame atomic absorption spectrophotometer]
• [Experience of ZHANG Jian-Qiu in treating "extraordinary meridian diseases" based on syndrome differentiation of miscellaneous diseases]
• [Experimental study on the myogenic differentiation of marrow mesenchymal stem cells in the local muscle tissues]
• [Expression, localization and interrelationship of P27kip1 and cyclin D3 in non-Hodgkin's lymphoma]
• [Pursue one's study and cultivate one's morality in scientific research]
• [Relation between activation of NF-kappa B and chemotherapy induced apoptosis of leukemic cells]
• [Relationship between myocyte proliferation and cardiac function in adult rats with heart failure]
• [Scatter correction of PET based on non-linear statistical estimate method]
• [Species composition and ecological distribution of planktonic diatoms in the Changjiang River estuary during spring]
• [Study on the cloning goat by cross-breed somatic cell nuclear transfer]
• [Study on the interaction of metal ion in active center of superoxide dismutase with cobalt chloride by visible spectroscopy]
• [Study on the relationship between Fas expression and apoptosis in oral squamous cell carcinoma]
• [The effects of interleukin-11 on high-dose methotrexate (HDMTX) induced mucositis in Wistar rats.]
• [The protective effect of basic fibroblast growth factor (bFGF) and electroacupuncture on neurons against cerebral ischemia]
• [The role of homeobox B2 gene in vascular endothelial proliferation and the protective effects of VEGF on the endothelia against radiation injury]