[Experimental study of coronary reactive hyperemia--effects of hypothermia and potassium cardioplegia]

[Experimental study of coronary reactive hyperemia--effects of hypothermia and potassium cardioplegia] Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

[Experimental study of coronary reactive hyperemia--effects of hypothermia and potassium cardioplegia] Abstract Text:

Y Umebayashi,

A hyperemic response on dog hearts following myocardial ischemia for 10 minutes has been studied in reference to myocardial protection with cardioplegia and hypothermia. Experimental animals were divided into four groups according to the difference in temperature and with or without cardioplegia during ischemia of the hearts. Group I (n = 7) succumbed to a normothermic ischemia. Group II (n = 6) had normothermic ischemia following infusion of 8 ml/kg of a normothermic cardioplegic solution. Group III (n = 7) had ischemia under moderate hypothermia (28 degrees C). Group IV [n = 7) had hypothermic ischemia following infusion of 8 ml/kg of hypothermic cardioplegic solution. A percent repayment of the flow debts in groups I, II, III, and IV were 234.6 +/- 38.3%, 101.5 +/- 40.8%, 134.5 +/- 50.0% and 112.8 +/- 36.5%, respectively. There was significant difference between group I and group II and IV (p less than 0.001) and group III (p less than 0.02). Peak flow in reactive hyperemia compared with control flow were 605.4 +/- 131.1%, 328.3 +/- 60.2%, 288.8 +/- 79.7% and 282.2 +/- 65.4% in each group I, II, III, and IV, respectively. The value in group I was significantly high in comparison with others (p less than 0.005). Depression of oxygen consumption was observed in groups with hypothermia as well as with cardioplegia. A hyperemic response was low in cardioplegia and/or hypothermia group. These data are suggestive of a beneficial use of cardioplegia and hypothermia on cardiac surgery through the observation of coronary reactive hyperemia after myocardial ischemia.

[Experimental study of coronary reactive hyperemia--effects of hypothermia and potassium cardioplegia] Publishing Authors By Initials

Y Umebayashi,

For similar inorganic chemicals: potassium compounds research abstracts see: inorganic chemicals: potassium compounds research

PUBMED ID PMID:

MEDLINE DATE:

[Experimental study of coronary reactive hyperemia--effects of hypothermia and potassium cardioplegia] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: [Zasshi] [Journal]. Nihon Ky?bu Geka Gakkai

VOLUME: 37

Page Numbers: 1901-7

Journal Abbreviation:

ISSN: 0369-4739

DAY: 14

MONTH: Sep

YEAR: 1989

[Experimental study of coronary reactive hyperemia--effects of hypothermia and potassium cardioplegia] Information

Number of References:

LANGUAGE: jpn

NlmUniqueID: 19130180

[Experimental study of coronary reactive hyperemia--effects of hypothermia and potassium cardioplegia] Keywords Mesh Terms:

KEYWORDS: Potassium Compounds

MESH TERMS: therapeutic use

Chemical & Substance for Abstract: [Experimental study of coronary reactive hyperemia--effects of hypothermia and potassium cardioplegia] Information

Substance Name: Potassium

Registry Number: 7440-09-7

Grant and Affiliation Information for [Experimental study of coronary reactive hyperemia--effects of hypothermia and potassium cardioplegia]

AFFILIATION:

Country: JAPAN

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Nippon Kyobu Geka Gakkai Zassh

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Experimental study of coronary reactive hyperemia--effects of hypothermia and potassium cardioplegia Related Publications

• [Experimental study of coronary reactive hyperemia--effects of hypothermia and potassium cardioplegia]