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Experience of retroperitoneoscopic adrenalectomy in 195 patients with primary aldosteronism.

Experience of retroperitoneoscopic adrenalectomy in 195 patients with primary aldosteronism. Research Abstract Details 

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  • Experience of retroperitoneoscopic adrenalectomy in 195 patients with primary aldosteronism. Abstract Text:

    yi linYi Lin,liming liLiming Li,jun zhuJun Zhu,wanming qiangWanming Qiang,kazuhide makiyamaKazuhide Makiyama,yoshinobu kubotaYoshinobu Kubota,yi linYi Lin,liming liLiming Li,jun zhuJun Zhu,wanming qiangWanming Qiang,kazuhide makiyamaKazuhide Makiyama,yoshinobu kubotaYoshinobu Kubota,

    OBJECTIVES: Laparoscopic adrenalectomy has become an effective option for aldosteronoma. We evaluated the retroperitoneal approach with regard to safety, efficacy, invasiveness and cost-benefit ratio in patients with primary aldosteronism. METHODS: Between July 1999 and June 2005, we carried out a total of 195 retroperitoneoscopic adrenalectomies (RA) in one hospital, including 108 on the left and 87 on the right, in 78 men and 113 women aged 20-78 years (mean age 48.2 years) with aldosteronoma. Average adrenal tumor size was 16 mm (range 10-32 mm). The 195 operations were divided into 10 groups of 20 operations each, and the mean duration and estimated blood loss for each group were compared. RESULTS: The mean operating time and intraoperative blood loss in RA were 93.2 +/- 37.4 (45-210) min and 68.5 +/- 53.2 (5-210) mL, respectively. Compared to group 1 (cases 1-20), a statistically significant decrease in operative time and estimated blood loss were seen in and after group 4 (>or= case 61, 94.5 +/- 30.3 vs 139.2 +/- 44.7 min, P < 0.01), and in and after group 5 (>or= case 81, 67.5 +/- 50.5 vs 120.5 +/- 60.9 mL, P < 0.01), respectively. No differences were found in duration of surgery and estimated blood loss between left and right sided tumors (P > 0.05). The mean postoperative hospital stay was 4.5 +/- 1.2 days. Postoperative complications, including hematoma and wound infection, occurred in 4.1% of patients. CONCLUSIONS: Retroperitoneoscopic adrenalectomy for aldosteronoma is a safe, effective, and minimally invasive approach with an advantageous cost-benefit ratio. With accumulated experience, it can expedite the learning curve for RA.

    Experience of retroperitoneoscopic adrenalectomy in 195 patients with primary aldosteronism. Publishing Authors By Initials

    y linY Lin,l liL Li,j zhuJ Zhu,w qiangW Qiang,k makiyamaK Makiyama,y kubotaY Kubota,y linY Lin,l liL Li,j zhuJ Zhu,w qiangW Qiang,k makiyamaK Makiyama,y kubotaY Kubota,

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    Experience of retroperitoneoscopic adrenalectomy in 195 patients with primary aldosteronism. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: International journal of urology : official journa

    VOLUME: 14

    Page Numbers: 910-3

    Journal Abbreviation: Int. J. Urol.

    ISSN: 0919-8172

    DAY: 20

    MONTH: Oct

    YEAR: 2007

    Experience of retroperitoneoscopic adrenalectomy in 195 patients with primary aldosteronism. Information

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    LANGUAGE: eng

    NlmUniqueID: 9440237

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    AFFILIATION: Department of Urology, Tianjin Medical University General Hospital, Institute of Urology, Tianjin, China. linyi6312@hotmail.com

    Country: Australia

    Australia Research PublicationAustralia Research Publication

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    MEDLINETA: Int J Urol

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