Exercise training and sympathetic nervous system activity: evidence for physical activity dependent neural plasticity.

Exercise training and sympathetic nervous system activity: evidence for physical activity dependent neural plasticity. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Exercise training and sympathetic nervous system activity: evidence for physical activity dependent neural plasticity. Abstract Text:

Patrick J Mueller,

1. It has been generally accepted that regular physical activity is associated with beneficial effects on the cardiovascular system. In fact, the idea that exercise maintains cardiovascular health is evident by the direct links between a sedentary lifestyle and the risk of cardiovascular and other disease states. 2. Cardiovascular diseases, such as hypertension and heart failure, are often associated with sympathetic nervous system (SNS) overactivity. Conversely, exercise has been shown to reduce hypertension and decrease elevated SNS activity. In addition, there is evidence that exercise may reduce resting blood pressure and sympathetic outflow in normal individuals. 3. Although somewhat controversial in humans, evidence from animal studies also indicates that exercise training reduces baroreflex-mediated and other forms of sympathoexcitation in normal individuals. Collectively, these data are consistent with the hypothesis that physical activity may decrease, and physical inactivity may increase, the incidence of cardiovascular disease via alterations in SNS activity. Despite the important clinical implications of this possibility, the mechanisms by which exercise alters control of SNS activity remain to be fully elucidated. 4. Recent evidence suggests that central nervous system (CNS) plasticity occurs under a variety of conditions, including varying levels of physical activity. The purpose of the present brief review is to provide evidence that changes within the CNS contribute importantly to altered regulation of the SNS observed following exercise training. The primary hypothesis is that physical activity versus inactivity produces plasticity within neural networks that regulate SNS activity. This hypothesis is supported by published and preliminary data that suggest that exercise training may reduce sympathoexcitation by reducing activation of neurons within cardiovascular regions of the brain. These mechanisms are likely to be important in disease states of sympathetic overactivity and in normal healthy individuals whose risk of cardiovascular disease is reduced by leading an active versus sedentary lifestyle.

Exercise training and sympathetic nervous system activity: evidence for physical activity dependent neural plasticity. Publishing Authors By Initials

PJ Mueller,

For similar nervous system: peripheral nervous system: autonomic nervous system: sympathetic nervous system research abstracts see: nervous system: peripheral nervous system: autonomic nervous system: sympathetic nervous system research

PUBMED ID PMID:

MEDLINE DATE:

Exercise training and sympathetic nervous system activity: evidence for physical activity dependent neural plasticity. Journal Published:

PUBLICATION TYPE: Review

Journal: Clinical and experimental pharmacology & physiolog

VOLUME: 34

Page Numbers: 377-84

Journal Abbreviation: Clin. Exp. Pharmacol. Physiol.

ISSN: 0305-1870

DAY: 3

MONTH: Apr

YEAR: 2007

Exercise training and sympathetic nervous system activity: evidence for physical activity dependent neural plasticity. Information

Number of References: 91

LANGUAGE: eng

NlmUniqueID: 425076

Exercise training and sympathetic nervous system activity: evidence for physical activity dependent neural plasticity. Keywords Mesh Terms:

KEYWORDS: Sympathetic Nervous System

MESH TERMS: physiology

Chemical & Substance for Abstract: Exercise training and sympathetic nervous system activity: evidence for physical activity dependent neural plasticity. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Exercise training and sympathetic nervous system activity: evidence for physical activity dependent neural plasticity.

AFFILIATION: Dalton Cardiovascular Research Center and Department of Biomedical Sciences, University of Missouri-Columbia, Columbia, MO, USA. pmueller@med.wayne.edu

Country: Australia

AGENCY: United States NHLBI

GRANT: HL 55306

ACRONYM: HL

MEDLINETA: Clin Exp Pharmacol Physiol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Exercise training and sympathetic nervous system activity: evidence for physical activity dependent neural plasticity Related Publications

• A case report of Clarkson's disease: If you don't know it, you'll miss it.
• Algorithms for on-line Differentiation of Neuroelectric Activities.
• Allopeptide-specific CD4(+) T cells facilitate the differentiation of directly alloreactive graft-infiltrating CD8(+) T Cells.
• An open trial of levetiracetam for segmental and generalized dystonia.
• Direct evidence for enzyme persulfide and disulfide intermediates during 4-thiouridine biosynthesis.
• Dosage in the treatment of pollinosis.
• Effect of footwear and orthotic devices on stress reduction and soft tissue strain of the neuropathic foot.
• Exercise training and sympathetic nervous system activity: evidence for physical activity dependent neural plasticity.
• Exercise training attenuates increases in lumbar sympathetic nerve activity produced by stimulation of the rostral ventrolateral medulla.
• Lattice-based volumetric global illumination.
• Low sex hormone-binding globulin as a predictive marker for insulin resistance in women with hyperandrogenic syndrome.
• Mitochondrial genome integrity mutations uncouple the yeast Saccharomyces cerevisiae ATP synthase.
• Molecular recognition of BMP-2 and BMP receptor IA.
• Non-catalytic function for ATR in the checkpoint response.
• Novel features of the rotary catalytic mechanism revealed in the structure of yeast F1 ATPase.
• Numerical simulation of the plantar pressure distribution in the diabetic foot during the push-off stance.
• Oleamide synthesizing activity from rat kidney: identification as cytochrome c.
• On the hemolytic and thrombogenic potential of occluder prosthetic heart valves from in-vitro measurements.
• Pioglitazone: an anti-diabetic compound with anti-aging properties.
• Real-time 3D computed tomographic reconstruction using commodity graphics hardware.
• TREM-1--expressing intestinal macrophages crucially amplify chronic inflammation in experimental colitis and inflammatory bowel diseases.
• The DNA binding parvulin Par17 is targeted to the mitochondrial matrix by a recently evolved prepeptide uniquely present in Hominidae.
• The amide rotational barrier in isonicotinamide: Dynamic NMR and ab initio studies.
• The experience of rural independent pharmacies with medicare part D: reports from the field.
• The risk of malarial infections and disease in Papua New Guinean children.
• The use of B-type natriuretic peptides in the intensive care unit.
• Trace element removal during in vitro and in vivo continuous haemodialysis.
• Transcriptional dysregulation during myeloid transformation in AML.
• Vaccines against malaria - an update.
• Virus infection causes specific learning deficits in honeybee foragers.