Exchanges of membrane patches (trogocytosis) split theoretical and actual functions of immune cells.

Exchanges of membrane patches (trogocytosis) split theoretical and actual functions of immune cells. Research Abstract Details 

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Exchanges of membrane patches (trogocytosis) split theoretical and actual functions of immune cells. Abstract Text:

Joel LeMaoult,Julien Caumartin,Edgardo D Carosella,

Exchanges of antigens between immune cells have long been evidenced in the murine system and more recently in humans, but the mechanisms by which these transfers occur, and even more so their functional and physiologic significance remain unclear. Yet, intercellular antigen exchanges, and particularly intercellular exchanges of intact membrane patches, also called trogocytosis, have recently been the subject of renewed interest. Indeed, trogocytosis has been thoroughly investigated in terms of phenomenology, mechanisms and parameters, and function. For lack of a dramatic function for trogocytosis, the possible significance of membrane patch transfers has been discussed. Here, we will briefly outline the key findings concerning trogocytosis, highlight their significance, and discuss how they have an impact on commonly accepted immune mechanisms.

Exchanges of membrane patches (trogocytosis) split theoretical and actual functions of immune cells. Publishing Authors By Initials

J LeMaoult,J Caumartin,ED Carosella,

For similar hemic and immune systems: immune system research abstracts see: hemic and immune systems: immune system research

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Exchanges of membrane patches (trogocytosis) split theoretical and actual functions of immune cells. Journal Published:

PUBLICATION TYPE: Review

Journal: Human immunology

VOLUME: 68

Page Numbers: 240-3

Journal Abbreviation: Hum. Immunol.

ISSN: 0198-8859

DAY: 22

MONTH: 12

YEAR: 2006

Exchanges of membrane patches (trogocytosis) split theoretical and actual functions of immune cells. Information

Number of References: 28

LANGUAGE: eng

NlmUniqueID: 8010936

Exchanges of membrane patches (trogocytosis) split theoretical and actual functions of immune cells. Keywords Mesh Terms:

KEYWORDS: Immune System

MESH TERMS: physiology

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Grant and Affiliation Information for Exchanges of membrane patches (trogocytosis) split theoretical and actual functions of immune cells.

AFFILIATION: Service de Recherches en Hémato-Immunologie, Commissariat a l'Energie Atomique, Hopital Saint Louis, Paris, France. Joel.LeMaoult@cea.fr

Country: United States

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MEDLINETA: Hum Immunol

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