Evolutionary change in the insulin receptors of hystricomorph rodents.

Evolutionary change in the insulin receptors of hystricomorph rodents. Research Abstract Details 

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Evolutionary change in the insulin receptors of hystricomorph rodents. Abstract Text:

R Horuk,P Goodwin,K O'connor,R W Neville,N R Lazarus,D Stone,

INSULIN receptors have been thought to have remained unaltered despite evolutionary changes in the hormone(1). Because insulins from hystricomorph rodents are known to be highly substituted compared with other mammalian insulins, we decided to investigate the insulin receptor of some hystricomorphs to determine whether evolutionary change had occurred within the receptor itself. Here we present the first evidence that hystricomorph rodent insulin receptors have undergone evolutionary change.

Evolutionary change in the insulin receptors of hystricomorph rodents. Publishing Authors By Initials

R Horuk,P Goodwin,K O'connor,RW Neville,NR Lazarus,D Stone,

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Evolutionary change in the insulin receptors of hystricomorph rodents. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Nature

VOLUME: 279

Page Numbers: 439-40

Journal Abbreviation: Nature

ISSN: 0028-0836

DAY: 31

MONTH: May

YEAR: 1979

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LANGUAGE: eng

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