Evidence of slow maturation of the superior longitudinal fasciculus in early childhood by diffusion tensor imaging.

Evidence of slow maturation of the superior longitudinal fasciculus in early childhood by diffusion tensor imaging. Research Abstract Details 

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Evidence of slow maturation of the superior longitudinal fasciculus in early childhood by diffusion tensor imaging. Abstract Text:

Jiangyang Zhang,Alan Evans,Laurent Hermoye,Seung-Koo Lee,Setsu Wakana,Weihong Zhang,Pamela Donohue,Michael I Miller,Hao Huang,Xiaoqing Wang,Peter C M van Zijl,Susumu Mori,Jiangyang Zhang,Alan Evans,Laurent Hermoye,Seung-Koo Lee,Setsu Wakana,Weihong Zhang,Pamela Donohue,Michael I Miller,Hao Huang,Xiaoqing Wang,Peter C M van Zijl,Susumu Mori,

While the majority of axonal organization is established by birth in mammalian brains, axonal wiring and pruning processes, as well as myelination, are known to extend to the postnatal periods, where environmental stimuli often play a major role. Normal axonal and myelin development of individual white matter tracts of human in this period is poorly understood and may have a major role in cognitive development of human. In this study, we applied diffusion tensor imaging and normalization-based population analyses to 44 preteen children and 30 adult images. We observed highly significant changes of fiber orientations at regions that correspond to the superior longitudinal fasciculus during the first 5 years. The result is attributed to slow axonal and/or myelin maturation of this tract, which is believed to be involved in language functions.

Evidence of slow maturation of the superior longitudinal fasciculus in early childhood by diffusion tensor imaging. Publishing Authors By Initials

J Zhang,A Evans,L Hermoye,SK Lee,S Wakana,W Zhang,P Donohue,MI Miller,H Huang,X Wang,PC van Zijl,S Mori,J Zhang,A Evans,L Hermoye,SK Lee,S Wakana,W Zhang,P Donohue,MI Miller,H Huang,X Wang,PC van Zijl,S Mori,

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Evidence of slow maturation of the superior longitudinal fasciculus in early childhood by diffusion tensor imaging. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: NeuroImage

VOLUME: 38

Page Numbers: 239-47

Journal Abbreviation: Neuroimage

ISSN: 1053-8119

DAY: 8

MONTH: 08

YEAR: 2007

Evidence of slow maturation of the superior longitudinal fasciculus in early childhood by diffusion tensor imaging. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Evidence of slow maturation of the superior longitudinal fasciculus in early childhood by diffusion tensor imaging.

AFFILIATION: Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA, and Diagnostic Radiology Unit, Saint-Luc University Hospital, Brussels, Belgium.

Country: United States

AGENCY: United States NIA

GRANT: R01AG20012

ACRONYM: AG

MEDLINETA: Neuroimage

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