Evidence for existence of inactive arterial renin-like enzyme in the rat.

Evidence for existence of inactive arterial renin-like enzyme in the rat. Research Abstract Details 

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Evidence for existence of inactive arterial renin-like enzyme in the rat. Abstract Text:

K Mizuno,M Gotoh,S Hashimoto,S Fukuchi,

Inactive renin-like enzyme(s) in the arterial wall of the rat are converted to active renin-like enzyme in vitro by either "acid activation" (dialysis to pH 3.3 followed by dialysis to pH 7.4) or "protease-induced activation" (trypsin, alpha-chymotrypsin and glandular kallikrein). The molecular weights of the inactive renin-like enzyme(s) before trypsin activation were estimated to be about 68,000, 44,000, 36,000 and 30,000 by column chromatography. These findings may offer a new aspect for the role of the arterial renin-angiotensin system in the local control of vascular tone by interconversion of the inactive to the active renin-like enzymes in the arterial wall.

Evidence for existence of inactive arterial renin-like enzyme in the rat. Publishing Authors By Initials

K Mizuno,M Gotoh,S Hashimoto,S Fukuchi,

For similar biochemical phenomena, metabolism, and nutrition: metabolism: renin-angiotensin system research abstracts see: biochemical phenomena, metabolism, and nutrition: metabolism: renin-angiotensin system research

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Evidence for existence of inactive arterial renin-like enzyme in the rat. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Clinical and experimental hypertension. Part A, Th

VOLUME: 7

Page Numbers: 93-103

Journal Abbreviation:

ISSN: 0730-0077

DAY: 12

MONTH: 02

YEAR: 1985

Evidence for existence of inactive arterial renin-like enzyme in the rat. Information

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LANGUAGE: eng

NlmUniqueID: 8207790

Evidence for existence of inactive arterial renin-like enzyme in the rat. Keywords Mesh Terms:

KEYWORDS: Renin-Angiotensin System

MESH TERMS: metabolism

Chemical & Substance for Abstract: Evidence for existence of inactive arterial renin-like enzyme in the rat. Information

Substance Name: Renin

Registry Number: EC 3.4.23.15

Grant and Affiliation Information for Evidence for existence of inactive arterial renin-like enzyme in the rat.

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Country: UNITED STATES

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MEDLINETA: Clin Exp Hypertens A

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