[Evaluation of urinary ortho-cresol as biological monitoring indicator of occupational exposure to toluene]

[Evaluation of urinary ortho-cresol as biological monitoring indicator of occupational exposure to toluene] Research Abstract Details 

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[Evaluation of urinary ortho-cresol as biological monitoring indicator of occupational exposure to toluene] Abstract Text:

Yaxian Mi,Daili Liu,Zhihua Li,Jianguo Li,Yi Luo,Jian Hu,

OBJECTIVE: To investigate the feasibility of urinary ortho-cresol levels as a biological monitoring indicator for toluene exposure. METHODS: Establish pre-column derivation HPLC method to detect ortho-cresol levels in urine of human body. Ortho-cresol levels in urine of workers non-exposed and exposed to toluene was examined using this pre-column derivation HPLC method, and exposure assessment was conducted. RESULTS: It was shown that urinary ortho-cresol level in exposed workers was (2.61 +/- 1.94) mg/L, higher than those of control group [(0.32 +/- 0.23) mg/L, P < 0.001]. Urinary ortho-cresol level in exposed workers at the end of a workshift was higher than those before exposure to toluene, and also was correlated with the concentration of toluene to which individual exposed(r = 0.6295, P < 0.01). CONCLUSION: Urinary ortho-cresol as a biological monitoring indicator for toluene exposure is feasible.

[Evaluation of urinary ortho-cresol as biological monitoring indicator of occupational exposure to toluene] Publishing Authors By Initials

Y Mi,D Liu,Z Li,J Li,Y Luo,J Hu,

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[Evaluation of urinary ortho-cresol as biological monitoring indicator of occupational exposure to toluene] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Z

VOLUME: 20

Page Numbers: 200-2

Journal Abbreviation: Zhonghua Lao Dong Wei Sheng Zh

ISSN: 1001-9391

DAY: 25

MONTH: Jun

YEAR: 2002

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LANGUAGE: chi

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AFFILIATION: Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China.

Country: China

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MEDLINETA: Zhonghua Lao Dong Wei Sheng Zh

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