Evaluation of carotid endarterectomy with sequential MR perfusion imaging: a preliminary report.

Evaluation of carotid endarterectomy with sequential MR perfusion imaging: a preliminary report. Research Abstract Details 

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Evaluation of carotid endarterectomy with sequential MR perfusion imaging: a preliminary report. Abstract Text:

J H Gillard,C R Hardingham,P J Kirkpatrick,N M Antoun,C E Freer,P D Griffiths,

BACKGROUND AND PURPOSE: Current indications for carotid endarterectomy are determined by balancing the relative risks of surgery with the benefits of reduced risk of subsequent stroke. Our purpose was to use MR perfusion imaging to assess patients being considered for carotid endarterectomy and to monitor sequential changes in MR perfusion characteristics after surgery. In particular, we wished to determine whether this technique could be used to detect changes that might be related to post-carotid endarterectomy hyperemia. METHODS: We used a single-section gradient-recalled echo sequence to investigate 14 patients being examined before possible surgery for carotid artery disease. In the 12 patients in whom carotid endarterectomy was performed, sequential studies were performed 3 to 5 days after surgery and at 3 months. Analysis of bolus-arrival-time (BAT) images was performed. RESULTS: Significant delays in preoperative BAT images of 0.89 seconds (range, 0.05 to 3.22 seconds) were apparent between hemispheres. Excluding the two patients with contralateral internal carotid artery (ICA) occlusion, early arrival, possibly indicating postoperative hyperemia, was seen in five patients immediately after carotid endarterectomy but resolved within 3 to 5 months after surgery. CONCLUSION: MR perfusion imaging shows differences in BAT between hemispheres in patients with ICA stenosis. Changes in perfusion characteristics after carotid endarterectomy are complex, and early BAT on the operative side can occur soon after endarterectomy in over half those patients without an occluded contralateral vessel. The significance of these findings with regard to patient outcome and risk of postoperative hyperemia requires further investigation.

Evaluation of carotid endarterectomy with sequential MR perfusion imaging: a preliminary report. Publishing Authors By Initials

JH Gillard,CR Hardingham,PJ Kirkpatrick,NM Antoun,CE Freer,PD Griffiths,

For similar surgical procedures, operative: postoperative period research abstracts see: surgical procedures, operative: postoperative period research

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Evaluation of carotid endarterectomy with sequential MR perfusion imaging: a preliminary report. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: AJNR. American journal of neuroradiology

VOLUME: 19

Page Numbers: 1747-52

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ISSN: 0195-6108

DAY: 14

MONTH: Oct

YEAR: 1998

Evaluation of carotid endarterectomy with sequential MR perfusion imaging: a preliminary report. Information

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LANGUAGE: eng

NlmUniqueID: 8003708

Evaluation of carotid endarterectomy with sequential MR perfusion imaging: a preliminary report. Keywords Mesh Terms:

KEYWORDS: Postoperative Period

MESH TERMS: methods

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Grant and Affiliation Information for Evaluation of carotid endarterectomy with sequential MR perfusion imaging: a preliminary report.

AFFILIATION: Department of Radiology, Addenbrooke's Hospital and University of Cambridge, United Kingdom.

Country: UNITED STATES

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MEDLINETA: AJNR Am J Neuroradiol

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