[Estimation of potential mutagenic activity of 24-epibrassinolide]

[Estimation of potential mutagenic activity of 24-epibrassinolide] Research Abstract Details 

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[Estimation of potential mutagenic activity of 24-epibrassinolide] Abstract Text:

A M Vo?tovich,L A Nadzharian,A I Kotelenets,V Iu Afonin,A G Davydovski?,A A Ushkov,N V Gavrilenko,

Genotoxic effect of synthetic phytohormone analogue of steroid origin epibrassinolide was studied in in vitro- and in vivo-tests. Epibrassinolide did not display mutagenic properties in Ames' test (S. typhimurium, TA100) and DNA damaging activity test (DNA of phage lambda). The rise in the level of polichromatophilous erythrocytes with micronuclei was observed in the micronuclear test at intraperitoneal epibrassinolide injection at the dose of 500 mg/kg that seems to be associated with disturbance of cell membrane permeability.

[Estimation of potential mutagenic activity of 24-epibrassinolide] Publishing Authors By Initials

AM Vo?tovich,LA Nadzharian,AI Kotelenets,VIu Afonin,AG Davydovski?,AA Ushkov,NV Gavrilenko,

For similar polycyclic compounds: steroids: steroids, heterocyclic research abstracts see: polycyclic compounds: steroids: steroids, heterocyclic research

PUBMED ID PMID:

MEDLINE DATE: 2004 Nov-Dec

[Estimation of potential mutagenic activity of 24-epibrassinolide] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: T?Sitologii?a i genetika

VOLUME: 38

Page Numbers: 49-53

Journal Abbreviation: Tsitol. Genet.

ISSN: 0564-3783

DAY: 15

MONTH: 02

YEAR: 2008

[Estimation of potential mutagenic activity of 24-epibrassinolide] Information

Number of References:

LANGUAGE: rus

NlmUniqueID: 101671

[Estimation of potential mutagenic activity of 24-epibrassinolide] Keywords Mesh Terms:

KEYWORDS: Steroids, Heterocyclic

MESH TERMS: toxicity

Chemical & Substance for Abstract: [Estimation of potential mutagenic activity of 24-epibrassinolide] Information

Substance Name: brassinolide

Registry Number: 72962-43-7

Grant and Affiliation Information for [Estimation of potential mutagenic activity of 24-epibrassinolide]

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Country: Ukraine

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MEDLINETA: Tsitol Genet

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