[Estimating the biological effect of detrimental substances on E. coli with flow microcalorimetry. I. Flow microcalorimetric test systems using microorganisms for antibiotics and chemicals (literature review)]

[Estimating the biological effect of detrimental substances on E. coli with flow microcalorimetry. I. Flow microcalorimetric test systems using microorganisms for antibiotics and chemicals (literature review)] Research Abstract Details 

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[Estimating the biological effect of detrimental substances on E. coli with flow microcalorimetry. I. Flow microcalorimetric test systems using microorganisms for antibiotics and chemicals (literature review)] Abstract Text:

Flow microcalorimetry has found increasing use in many rather different sections of biological science in order to investigate metabolic reactions accompanied by heat production during the last few years. The microcalorimetric technique seems to be adequate for investigating liquid microbial cultures, particularly. Flow microcalorimetry is preferentially used for testing the effect of antibiotics and to a smaller extend the effect of other chemical compounds on bacteria and yeasts. The test substances are usually added during the logarithmic growth phase of the microbial culture or to cultures of nongrowing cells in glucose buffer solution. There are less reports on the addition of the test substances during the steady heat plateau of a respiring or grown through culture. The received power-time-curves are compared to "control curves" recorded under identical conditions without test substances. Difficulties and errors can be caused by external influences (e.g. changes in room temperature) or by latent processes within the detector and tubes of the calorimeter (e.g. mixing reactions, ad- and desorption, adhesion to and growth on the walls of the tubes, obstruction by clots of cells). A substantial advantage of the microcalorimetric technique as compared to traditional bioassays is the continuous monitoring of the effect, an additional advantage is its quick and simple performance. The sensitivity is comparable to other bioassays of antibiotics.

[Estimating the biological effect of detrimental substances on E. coli with flow microcalorimetry. I. Flow microcalorimetric test systems using microorganisms for antibiotics and chemicals (literature review)] Publishing Authors By Initials

For similar fungi: yeasts research abstracts see: fungi: yeasts research

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[Estimating the biological effect of detrimental substances on E. coli with flow microcalorimetry. I. Flow microcalorimetric test systems using microorganisms for antibiotics and chemicals (literature review)] Journal Published:

PUBLICATION TYPE: Review

Journal: Zentralblatt für Bakteriologie, Mikrobiologie und

VOLUME: 183

Page Numbers: 36-46

Journal Abbreviation:

ISSN: 0932-6073

DAY: 26

MONTH: Dec

YEAR: 1986

[Estimating the biological effect of detrimental substances on E. coli with flow microcalorimetry. I. Flow microcalorimetric test systems using microorganisms for antibiotics and chemicals (literature review)] Information

Number of References: 56

LANGUAGE: ger

NlmUniqueID: 8606774

[Estimating the biological effect of detrimental substances on E. coli with flow microcalorimetry. I. Flow microcalorimetric test systems using microorganisms for antibiotics and chemicals (literature review)] Keywords Mesh Terms:

KEYWORDS: Yeasts

MESH TERMS: drug effects

Chemical & Substance for Abstract: [Estimating the biological effect of detrimental substances on E. coli with flow microcalorimetry. I. Flow microcalorimetric test systems using microorganisms for antibiotics and chemicals (literature review)] Information

Substance Name: Anti-Bacterial Agents

Registry Number: 0

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Country: GERMANY, WEST

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MEDLINETA: Zentralbl Bakteriol Mikrobiol

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