Establishment of External Quality Control Program for hs-CRP and Three-Year Follow-Up of the Performance for Precision and Accuracy.

Establishment of External Quality Control Program for hs-CRP and Three-Year Follow-Up of the Performance for Precision and Accuracy. Research Abstract Details 

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Establishment of External Quality Control Program for hs-CRP and Three-Year Follow-Up of the Performance for Precision and Accuracy. Abstract Text:

Masakazu Nakamura,Shinichi Sato,Takashi Shimamoto,Masakazu Nakamura,Shinichi Sato,Takashi Shimamoto,Masakazu Nakamura,Shinichi Sato,Takashi Shimamoto,

Aim: We established an external quality control (QC) program for high-sensitivity C-reactive protein (hs-CRP) for a collaborative epidemiological study.Methods: External QC was performed 3 times in 3 years to follow hs-CRP performance for precision and accuracy.Results: For precision, the mean coefficient of variation (CV) of the internal QC by 9 laboratories was 2.2% and 1.9% in the 1st and 2nd tests, respectively. The mean CV of the external QC by 4 laboratories was 2.7% in the three tests. The CV of both the internal and external QC satisfied the acceptable range specified by the AHA/CDC Scientific Statement, CV < 10%. For accuracy, the mean values of the 1st external QC by 9 laboratories were set as the consensus value and the acceptable range was set to within +/- 10% from it. The mean accuracy by 9 laboratories was 0.51% in the 2nd external QC. The mean accuracy by 4 laboratories was - 0.37% in the 3rd external QC. These findings demonstrated that the initial consensus value was valid in the continued external QC, and hs-CRP was stable for 3 years.Conclusion: We demonstrated both the precision and accuracy of hs-CRP by an external QC program applied for 3 years in a collaborative epidemiological study.

Establishment of External Quality Control Program for hs-CRP and Three-Year Follow-Up of the Performance for Precision and Accuracy. Publishing Authors By Initials

M Nakamura,S Sato,T Shimamoto,M Nakamura,S Sato,T Shimamoto,M Nakamura,S Sato,T Shimamoto,

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Establishment of External Quality Control Program for hs-CRP and Three-Year Follow-Up of the Performance for Precision and Accuracy. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of atherosclerosis and thrombosis

VOLUME: 14

Page Numbers: 287-93

Journal Abbreviation: J. Atheroscler. Thromb.

ISSN: 1340-3478

DAY: 17

MONTH: 12

YEAR: 2007

Establishment of External Quality Control Program for hs-CRP and Three-Year Follow-Up of the Performance for Precision and Accuracy. Information

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LANGUAGE: eng

NlmUniqueID: 9506298

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Grant and Affiliation Information for Establishment of External Quality Control Program for hs-CRP and Three-Year Follow-Up of the Performance for Precision and Accuracy.

AFFILIATION: Osaka Medical Center for Health Science and Promotion, CRMLN Lipid Reference Laboratory.

Country: Japan

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MEDLINETA: J Atheroscler Thromb

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