[Establishment and characterization of a neural stem cell line (RNSC-FMU 1) from rat brain]

[Establishment and characterization of a neural stem cell line (RNSC-FMU 1) from rat brain] Research Abstract Details 

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[Establishment and characterization of a neural stem cell line (RNSC-FMU 1) from rat brain] Abstract Text:

Zhi Hong Zheng,Jian Shi Hu,Ling Lin,Xiao Qing You,Qi Zhang,Jian Yin Lin,

A neural stem cell line (RNSC-FMU 1) from rat brain have been established successfully by isolating and culturing neural stem cells from newborn SD rat brain in vitro with free-serum medium and passaging with mechanical division. The cell line cultured can continuously generate in vitro for long-term and it is 21 months (>100 passages) so far. These cells keep the feature of neural stem cell and normal karyotype. These neural stem cells can be induced to differentiate into neurons, astrocytes and oligodendrocytes. The cells have an extensive self-renewal capacity; its doubling time of proliferation is about 20 h. The cells are also cryopreservable. Tumor formation is not observed in nude mice that explanted with the cells. This cell line is a good tool for research of neural stem cell.

[Establishment and characterization of a neural stem cell line (RNSC-FMU 1) from rat brain] Publishing Authors By Initials

ZH Zheng,JS Hu,L Lin,XQ You,Q Zhang,JY Lin,

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[Establishment and characterization of a neural stem cell line (RNSC-FMU 1) from rat brain] Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Shi yan sheng wu xue bao

VOLUME: 37

Page Numbers: 199-204

Journal Abbreviation: Shi Yan Sheng Wu Xue Bao

ISSN: 0001-5334

DAY: 24

MONTH: Jun

YEAR: 2004

[Establishment and characterization of a neural stem cell line (RNSC-FMU 1) from rat brain] Information

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LANGUAGE: chi

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Grant and Affiliation Information for [Establishment and characterization of a neural stem cell line (RNSC-FMU 1) from rat brain]

AFFILIATION: Research Center of Molecular Medicine, Fujian Medical University, Fuzhou 350004.

Country: China

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MEDLINETA: Shi Yan Sheng Wu Xue Bao

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