Erythema multiforme and Stevens-Johnson syndrome following radiotherapy.

Erythema multiforme and Stevens-Johnson syndrome following radiotherapy. Research Abstract Details 

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Erythema multiforme and Stevens-Johnson syndrome following radiotherapy. Abstract Text:

Tadamasa Yoshitake,Katsumasa Nakamura,Yoshiyuki Shioyama,Tomonari Sasaki,Saiji Ooga,Madoka Abe,Yusuke Urashima,Kazunori Urabe,Hiromi Terashima,Hiroshi Honda,Tadamasa Yoshitake,Katsumasa Nakamura,Yoshiyuki Shioyama,Tomonari Sasaki,Saiji Ooga,Madoka Abe,Yusuke Urashima,Kazunori Urabe,Hiromi Terashima,Hiroshi Honda,

Erythema multiforme (EM) and Stevens-Johnson syndrome (SJS) are thought to be hypersensitivity syndromes with various causes, and radiotherapy might be one of the causes of these syndromes. We herein report two cases of EM/SJS following radiotherapy. The first case was a 63-year-old woman with breast cancer. At the end of postoperative radiotherapy with 60 Gy, severe pruritic erythema appeared in the irradiated area and spread over the whole body. She was diagnosed with EM by a skin biopsy. The second case was a 77-year-old woman with uterine cervical cancer who underwent postoperative radiotherapy. At a dose of 30.6 Gy, pruritic redness appeared in the irradiated area and the precordial region, and it became widespread rapidly with polymorphic transformation. Although without any histological confirmation, SJS was strongly suspected because of her pruritic conjunctivitis. Because both patients were given medicines during irradiation, radiotherapy may not be the only cause of EM/SJS. However, it should be noted that radiotherapy might trigger EM/SJS.

Erythema multiforme and Stevens-Johnson syndrome following radiotherapy. Publishing Authors By Initials

T Yoshitake,K Nakamura,Y Shioyama,T Sasaki,S Ooga,M Abe,Y Urashima,K Urabe,H Terashima,H Honda,T Yoshitake,K Nakamura,Y Shioyama,T Sasaki,S Ooga,M Abe,Y Urashima,K Urabe,H Terashima,H Honda,

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Erythema multiforme and Stevens-Johnson syndrome following radiotherapy. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Radiation medicine

VOLUME: 25

Page Numbers: 27-30

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ISSN: 0288-2043

DAY: 25

MONTH: 01

YEAR: 2007

Erythema multiforme and Stevens-Johnson syndrome following radiotherapy. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Erythema multiforme and Stevens-Johnson syndrome following radiotherapy.

AFFILIATION: Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

Country: Japan

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MEDLINETA: Radiat Med

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