Eruptive xanthomas associated with olanzapine use.

Eruptive xanthomas associated with olanzapine use. Research Abstract Details 

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Eruptive xanthomas associated with olanzapine use. Abstract Text:

BACKGROUND: Since their introduction to the US market, atypical antipsychotic drugs, such as olanzapine, have been widely prescribed for the management of psychosis and have increasingly been used in dermatologic settings for the treatment of psychogenic dermatoses. Mild hyperglycemia and hypertriglyceridemia have been documented from the use of these medications, but the range of effects on metabolism and the effects on skin are poorly characterized. OBSERVETION: We describe 3 patients who developed eruptive xanthomas, 1 of whom had relative insulin insufficiency, after starting olanzapine therapy. These cases further support the association of severe dyslipidemia with olanzapine use in selected patients. CONCLUSION: With the increasing use of atypical antipsychotic agents in the dermatologic setting, the dyslipidemia that develops in association with olanzapine use emphasizes the need for periodic metabolic studies in high-risk patients.

Eruptive xanthomas associated with olanzapine use. Publishing Authors By Initials

For similar nutritional and metabolic diseases: metabolic diseases: lipid metabolism disorders: xanthomatosis research abstracts see: nutritional and metabolic diseases: metabolic diseases: lipid metabolism disorders: xanthomatosis research

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Eruptive xanthomas associated with olanzapine use. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Archives of dermatology

VOLUME: 139

Page Numbers: 1045-8

Journal Abbreviation: Arch Dermatol

ISSN: 0003-987X

DAY: 17

MONTH: Aug

YEAR: 2003

Eruptive xanthomas associated with olanzapine use. Information

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LANGUAGE: eng

NlmUniqueID: 372433

Eruptive xanthomas associated with olanzapine use. Keywords Mesh Terms:

KEYWORDS: Xanthomatosis

MESH TERMS: pathology

Chemical & Substance for Abstract: Eruptive xanthomas associated with olanzapine use. Information

Substance Name: Pirenzepine

Registry Number: 28797-61-7

Grant and Affiliation Information for Eruptive xanthomas associated with olanzapine use.

AFFILIATION: Department of Dermatology, Program in Epithelial Biology, Stanford University School of Medicine, Stanford, Calif. 94305, USA.

Country: United States

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MEDLINETA: Arch Dermatol

REFSOURCE: Arch Dermatol. 2004 May;140(5):617-8

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