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Epidemiological features of aplastic anaemia in Pakistan.

Epidemiological features of aplastic anaemia in Pakistan. Research Abstract Details 

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  • Epidemiological features of aplastic anaemia in Pakistan. Abstract Text:

    s n adilS N Adil,i a burneyI A Burney,g n kakepotoG N Kakepoto,m khurshidM Khurshid,

    OBJECTIVE: To complete the data on the demographic features of patients diagnosed to have aplastic anemia at a single institution over a 7.5 years period. METHODS: Demographic information was retrieved from the patients medical records retrospectively as well as prospectively of those patients who presented with features of aplastic anaemia. Their diagnosis was confirmed by performing a complete blood count and bone marrow trephine. RESULTS: One hundred and forty four patients were diagnosed to have aplastic anemia; there were 106 males and 38 females. Their ages ranged from 2 to 75 years, with a median of 17 years, 112 (77.7%) patients were below the age of 30 years. Severe aplastic anemia (SAA) was seen in 74 (51.4%), very severe (VSAA) in 24 (16.7%) and non-severe aplastic anemia (NSAA) in 46 (31.9%) patients. No obvious cause could be established for 74.3%. Thirteen patients admitted using drugs known to cause AA and one was a radiographer (9%). Out of 44 patients tested, 7 (15.9%) were found to have either hepatitis B virus markers or antibody to hepatitis C at the time of diagnosis of AA. However it was difficult to establish a cause and effect relationship with either drugs or viruses. CONCLUSION: Aplastic anaemia is found to occur mostly in young males. The most common type was idiopathic severe aplastic anaemia.

    Epidemiological features of aplastic anaemia in Pakistan. Publishing Authors By Initials

    sn adilSN Adil,ia burneyIA Burney,gn kakepotoGN Kakepoto,m khurshidM Khurshid,

    For similar investigative techniques: epidemiologic methods: epidemiologic study characteristics as topic: epidemiologic studies: case-control studies: retrospective studies research abstracts see: investigative techniques: epidemiologic methods: epidemiologic study characteristics as topic: epidemiologic studies: case-control studies: retrospective studies research

    PUBMED ID PMID:

    MEDLINE DATE:

    Epidemiological features of aplastic anaemia in Pakistan. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: JPMA. The Journal of the Pakistan Medical Associat

    VOLUME: 51

    Page Numbers: 443-5

    Journal Abbreviation:

    ISSN: 0030-9982

    DAY: 12

    MONTH: Dec

    YEAR: 2001

    Epidemiological features of aplastic anaemia in Pakistan. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 7501162

    Epidemiological features of aplastic anaemia in Pakistan. Keywords Mesh Terms:

    KEYWORDS: Retrospective Studies

    MESH TERMS: epidemiology

    Chemical & Substance for Abstract: Epidemiological features of aplastic anaemia in Pakistan. Information

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    Grant and Affiliation Information for Epidemiological features of aplastic anaemia in Pakistan.

    AFFILIATION: Department of Pathology, Aga Khan University Hospital, Karachi.

    Country: Pakistan

    Pakistan Research PublicationPakistan Research Publication

    AGENCY:

    GRANT:

    ACRONYM:

    MEDLINETA: J Pak Med Assoc

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