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Enzyme inhibitors are not helpful in preserving big renin in the rat kidney.

Enzyme inhibitors are not helpful in preserving big renin in the rat kidney. Research Abstract Details 

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  • Enzyme inhibitors are not helpful in preserving big renin in the rat kidney. Abstract Text:

    i rubinI Rubin,e lauritzenE Lauritzen,

    The effect of four different homogenization methods, proteolytic enzymes and enzyme inhibitors on rat renal renin was studied. Rat kidney homogenate was treated with trypsin or pepsin. Neither of these enzymes had any effect on the molecular weight pattern. Enzyme inhibitors, 10 mM N-ethylmaleimide, 5.4 mM EDTA, 1.0 mM toluenesulfonyl fluoride, 2.3 mM o-phenanthroline, 2.3 mM p-hydroxymercuribenzoate, which was added to the homogenization medium, all or some of them, as well as 1/20 to the buffer solution used throughout the experiments for dialysis and column chromatography, did not alter the molecular weight pattern. These results suggest that renins, with molecular weights from above 60 000 Dalton to 37 000 Dalton were preformed in the rat kidney and extracted in a native form.

    Enzyme inhibitors are not helpful in preserving big renin in the rat kidney. Publishing Authors By Initials

    i rubinI Rubin,e lauritzenE Lauritzen,

    For similar enzymes and coenzymes: enzymes: hydrolases: peptide hydrolases: endopeptidases: aspartic endopeptidases: renin research abstracts see: enzymes and coenzymes: enzymes: hydrolases: peptide hydrolases: endopeptidases: aspartic endopeptidases: renin research

    PUBMED ID PMID:

    MEDLINE DATE:

    Enzyme inhibitors are not helpful in preserving big renin in the rat kidney. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Clinical and experimental hypertension. Part A, Th

    VOLUME: 4

    Page Numbers: 2107-20

    Journal Abbreviation:

    ISSN: 0730-0077

    DAY: 12

    MONTH: 02

    YEAR: 1982

    Enzyme inhibitors are not helpful in preserving big renin in the rat kidney. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 8207790

    Enzyme inhibitors are not helpful in preserving big renin in the rat kidney. Keywords Mesh Terms:

    KEYWORDS: Renin

    MESH TERMS: metabolism

    Chemical & Substance for Abstract: Enzyme inhibitors are not helpful in preserving big renin in the rat kidney. Information

    Substance Name: Renin

    Registry Number: EC 3.4.23.15

    Grant and Affiliation Information for Enzyme inhibitors are not helpful in preserving big renin in the rat kidney.

    AFFILIATION:

    Country: UNITED STATES

    UNITED STATES Research PublicationUNITED STATES Research Publication

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    GRANT:

    ACRONYM:

    MEDLINETA: Clin Exp Hypertens A

    REFSOURCE:

    DATABASENAME:

    ACCESSION NUMBER:

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